| Title |
Newborn Screening for SCID Identifies Patients with Ataxia Telangiectasia
|
|---|---|
| Published in |
Journal of Clinical Immunology, December 2012
|
| DOI | 10.1007/s10875-012-9846-1 |
| Pubmed ID | |
| Authors |
Jacob Mallott, Antonia Kwan, Joseph Church, Diana Gonzalez-Espinosa, Fred Lorey, Ling Fung Tang, Uma Sunderam, Sadhna Rana, Rajgopal Srinivasan, Steven E. Brenner, Jennifer Puck |
| Abstract |
Severe combined immunodeficiency (SCID) is characterized by failure of T lymphocyte development and absent or very low T cell receptor excision circles (TRECs), DNA byproducts of T cell maturation. Newborn screening for TRECs to identify SCID is now performed in several states using PCR of DNA from universally collected dried blood spots (DBS). In addition to infants with typical SCID, TREC screening identifies infants with T lymphocytopenia who appear healthy and in whom a SCID diagnosis cannot be confirmed. Deep sequencing was employed to find causes of T lymphocytopenia in such infants. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Spain | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 76 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Mexico | 1 | 1% |
| Spain | 1 | 1% |
| Russia | 1 | 1% |
| Unknown | 73 | 96% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 14 | 18% |
| Student > Ph. D. Student | 8 | 11% |
| Student > Postgraduate | 7 | 9% |
| Student > Bachelor | 7 | 9% |
| Other | 6 | 8% |
| Other | 19 | 25% |
| Unknown | 15 | 20% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 26 | 34% |
| Biochemistry, Genetics and Molecular Biology | 14 | 18% |
| Agricultural and Biological Sciences | 11 | 14% |
| Computer Science | 3 | 4% |
| Nursing and Health Professions | 2 | 3% |
| Other | 3 | 4% |
| Unknown | 17 | 22% |
Attention Score in Context
This research output has an Altmetric Attention Score of 17. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 17 April 2015.
All research outputs
#1,809,771
of 22,691,736 outputs
Outputs from Journal of Clinical Immunology
#72
of 1,559 outputs
Outputs of similar age
#18,299
of 280,184 outputs
Outputs of similar age from Journal of Clinical Immunology
#1
of 25 outputs
Altmetric has tracked 22,691,736 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 92nd percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,559 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.3. This one has done particularly well, scoring higher than 95% of its peers.
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We're also able to compare this research output to 25 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 96% of its contemporaries.