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Antigenic characterization of recent H5N1 highly pathogenic avian influenza viruses circulating in Egyptian poultry

Overview of attention for article published in Virology, November 2012
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Title
Antigenic characterization of recent H5N1 highly pathogenic avian influenza viruses circulating in Egyptian poultry
Published in
Virology, November 2012
DOI 10.1016/j.virol.2012.09.016
Pubmed ID
Authors

Maria Serena Beato, Marzia Mancin, Jialiang Yang, Alessandra Buratin, Marco Ruffa, Silvia Maniero, Alice Fusaro, Calogero Terregino, Xiu-Feng Wan, Ilaria Capua

Abstract

The extensive circulation of Highly Pathogenic (HP) H5N1 Avian Influenza in Egypt in poultry since 2006 resulted in the emergence of distinct clades with the recent identification of a further clade: 2.2.1.1. The aim of this study was to characterize for the first time the antigenic profile of an extensive collection of genetically diverse Egyptian H5N1 HP viruses isolated between 2007 and 2010 applying antigenic cartography and principal component analysis to serological data. We identified that Egyptian H5N1 viruses have undergone significant antigenic diversification between 2007 and 2010 and two distinct antigenic clusters co-circulated in 2010. Such clusters correlated with 2.2.1 and 2.2.1.1 clades, showing for the first time that the new emerging clade 2.2.1.1 is antigenically distinct. This study highlights that the antigenic diversity of H5N1 HP Egyptian viruses may represent a potential challenge for the development of an effective vaccination programme for animal and human health in Egypt.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 44 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Italy 1 2%
Egypt 1 2%
Unknown 42 95%

Demographic breakdown

Readers by professional status Count As %
Researcher 12 27%
Student > Ph. D. Student 6 14%
Student > Master 5 11%
Student > Doctoral Student 3 7%
Student > Bachelor 3 7%
Other 8 18%
Unknown 7 16%
Readers by discipline Count As %
Agricultural and Biological Sciences 10 23%
Veterinary Science and Veterinary Medicine 6 14%
Medicine and Dentistry 6 14%
Biochemistry, Genetics and Molecular Biology 2 5%
Immunology and Microbiology 2 5%
Other 9 20%
Unknown 9 20%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 31 December 2012.
All research outputs
#20,656,161
of 25,374,647 outputs
Outputs from Virology
#8,745
of 9,498 outputs
Outputs of similar age
#157,691
of 201,751 outputs
Outputs of similar age from Virology
#53
of 58 outputs
Altmetric has tracked 25,374,647 research outputs across all sources so far. This one is in the 10th percentile – i.e., 10% of other outputs scored the same or lower than it.
So far Altmetric has tracked 9,498 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.6. This one is in the 4th percentile – i.e., 4% of its peers scored the same or lower than it.
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We're also able to compare this research output to 58 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.