Title |
A Common Genetic Factor Explains the Covariation Among ADHD ODD and CD Symptoms in 9–10 Year Old Boys and Girls
|
---|---|
Published in |
Research on Child and Adolescent Psychopathology, November 2008
|
DOI | 10.1007/s10802-008-9278-9 |
Pubmed ID | |
Authors |
Catherine Tuvblad, Mo Zheng, Adrian Raine, Laura A. Baker |
Abstract |
Previous studies examining the covariation among Attention Deficit Hyperactivity Disorder (ADHD), Oppositional Defiant Disorder (ODD) and Conduct Disorder (CD) have yielded inconsistent results. Some studies have concluded that the covariation among these symptoms is due to common genetic influences, whereas others have found a common environmental overlap. The present study investigated the genetic and environmental correlations among these three childhood disorders, based on a sample of 1,219 twins, age 9-10 years. A latent externalizing behavior factor was found to explain the covariance among ADHD, ODD and CD symptoms. Genetic influences explained more than half of the variance in this externalizing factor in both boys and girls. There were also unique genetic and environmental influences in each set of symptoms, suggesting some etiological independence of the three disorders. Our findings have implications for molecular genetic studies trying to identify susceptibility genes for these disorders. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Japan | 1 | 33% |
Unknown | 2 | 67% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 3 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Netherlands | 1 | <1% |
United States | 1 | <1% |
Sweden | 1 | <1% |
Canada | 1 | <1% |
Unknown | 116 | 97% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 22 | 18% |
Student > Bachelor | 15 | 13% |
Student > Master | 14 | 12% |
Student > Doctoral Student | 10 | 8% |
Researcher | 9 | 8% |
Other | 26 | 22% |
Unknown | 24 | 20% |
Readers by discipline | Count | As % |
---|---|---|
Psychology | 57 | 48% |
Medicine and Dentistry | 12 | 10% |
Agricultural and Biological Sciences | 8 | 7% |
Social Sciences | 6 | 5% |
Nursing and Health Professions | 2 | 2% |
Other | 7 | 6% |
Unknown | 28 | 23% |