| Title |
The potter’s wheel: the host’s role in sculpting its microbiota
|
|---|---|
| Published in |
Cellular and Molecular Life Sciences, October 2011
|
| DOI | 10.1007/s00018-011-0830-3 |
| Pubmed ID | |
| Authors |
Charles L. Bevins, Nita H. Salzman |
| Abstract |
Animals, ranging from basal metazoans to primates, are host to complex microbial ecosystems; engaged in a symbiotic relationship that is essential for host physiology and homeostasis. Epithelial surfaces vary in the composition of colonizing microbiota as one compares anatomic sites, developmental stages and species origin. Alterations of microbial composition likely contribute to susceptibility to several distinct diseases. The forces that shape the colonizing microbial composition are the focus of much current investigation, and it is evident that there are pressures exerted both by the host and the external environment to mold these ecosystems. The focus of this review is to discuss recent studies that demonstrate the critical importance of host factors in selecting for its microbiome. Greater insight into host-microbiome interactions will be essential for understanding homeostasis at mucosal surfaces, and developing useful interventions when homeostasis is disrupted. |
Mendeley readers
The data shown below were compiled from readership statistics for 182 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 9 | 5% |
| United Kingdom | 4 | 2% |
| France | 1 | <1% |
| Germany | 1 | <1% |
| Unknown | 167 | 92% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 50 | 27% |
| Researcher | 40 | 22% |
| Student > Bachelor | 18 | 10% |
| Student > Master | 17 | 9% |
| Professor | 9 | 5% |
| Other | 32 | 18% |
| Unknown | 16 | 9% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 103 | 57% |
| Biochemistry, Genetics and Molecular Biology | 19 | 10% |
| Medicine and Dentistry | 14 | 8% |
| Immunology and Microbiology | 12 | 7% |
| Environmental Science | 5 | 3% |
| Other | 13 | 7% |
| Unknown | 16 | 9% |
Attention Score in Context
This research output has an Altmetric Attention Score of 15. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 12 August 2015.
All research outputs
#2,226,385
of 23,794,258 outputs
Outputs from Cellular and Molecular Life Sciences
#271
of 4,151 outputs
Outputs of similar age
#11,249
of 134,942 outputs
Outputs of similar age from Cellular and Molecular Life Sciences
#4
of 40 outputs
Altmetric has tracked 23,794,258 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 90th percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 4,151 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.0. This one has done particularly well, scoring higher than 99% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 134,942 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 91% of its contemporaries.
We're also able to compare this research output to 40 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 90% of its contemporaries.