Title |
The Effect of Zinc Supplementation on Insulin Resistance in Obese Subjects: a Systematic Review
|
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Published in |
Biological Trace Element Research, September 2016
|
DOI | 10.1007/s12011-016-0835-8 |
Pubmed ID | |
Authors |
Kyria Jayanne Clímaco Cruz, Jennifer Beatriz Silva Morais, Ana Raquel Soares de Oliveira, Juliana Soares Severo, Dilina do Nascimento Marreiro |
Abstract |
Obesity is a chronic disease characterized by excessive accumulation of body fat and the presence of metabolic disorders such as insulin resistance. In this sense, zinc is an important nutrient that stimulates insulin secretion and increases sensitivity to insulin. The aim of this study was to investigate the effect of zinc supplementation on insulin resistance in obese subjects through a systematic review of the available clinical trials. The search for articles was conducted using the PubMed, SciVerse Scopus, SciVerse ScienceDirect, and Cochrane databases, on May 25, 2016, by two authors independently. The recommendations of the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) were followed in the conduct of this review. The Cochrane Collaboration tool was used to assess the risk of bias of the trials included in this review. After screening of the articles, six clinical trials were included in this systematic review. The scientific evidence presented in this systematic review shows that zinc supplementation improves insulin resistance in obese individuals of both sexes. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Ireland | 1 | 25% |
Australia | 1 | 25% |
United States | 1 | 25% |
Brazil | 1 | 25% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 2 | 50% |
Practitioners (doctors, other healthcare professionals) | 1 | 25% |
Scientists | 1 | 25% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 66 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 14 | 21% |
Student > Master | 11 | 17% |
Other | 6 | 9% |
Student > Bachelor | 5 | 8% |
Student > Doctoral Student | 4 | 6% |
Other | 7 | 11% |
Unknown | 19 | 29% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 16 | 24% |
Nursing and Health Professions | 10 | 15% |
Agricultural and Biological Sciences | 8 | 12% |
Veterinary Science and Veterinary Medicine | 2 | 3% |
Pharmacology, Toxicology and Pharmaceutical Science | 2 | 3% |
Other | 10 | 15% |
Unknown | 18 | 27% |