Title |
Response of human chondrocytes and mesenchymal stromal cells to a decellularized human dermis
|
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Published in |
BMC Musculoskeletal Disorders, January 2013
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DOI | 10.1186/1471-2474-14-12 |
Pubmed ID | |
Authors |
Gianluca Giavaresi, Elena Bondioli, Davide Melandri, Roberto Giardino, Matilde Tschon, Paola Torricelli, Giovanna Cenacchi, Roberto Rotini, Alessandro Castagna, Francesca Veronesi, Stefania Pagani, Milena Fini |
Abstract |
Although progress has been made in the treatment of articular cartilage lesions, they are still a major challenge because current techniques do not provide satisfactory long-term outcomes. Tissue engineering and the use of functional biomaterials might be an alternative regenerative strategy and fulfill clinical needs. Decellularized extracellular matrices have generated interest as functional biologic scaffolds, but there are few studies on cartilage regeneration. The aim of this study was to evaluate in vitro the biological influence of a newly developed decellularized human dermal extracellular matrix on two human primary cultures. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United Kingdom | 1 | 2% |
Unknown | 52 | 98% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 9 | 17% |
Student > Bachelor | 9 | 17% |
Researcher | 9 | 17% |
Student > Master | 8 | 15% |
Student > Doctoral Student | 3 | 6% |
Other | 5 | 9% |
Unknown | 10 | 19% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 14 | 26% |
Agricultural and Biological Sciences | 14 | 26% |
Biochemistry, Genetics and Molecular Biology | 4 | 8% |
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Chemical Engineering | 2 | 4% |
Other | 4 | 8% |
Unknown | 12 | 23% |