Title |
Genome-based insights into the resistome and mobilome of multidrug-resistant Aeromonas sp. ARM81 isolated from wastewater
|
---|---|
Published in |
Archives of Microbiology, September 2016
|
DOI | 10.1007/s00203-016-1285-6 |
Pubmed ID | |
Authors |
Marcin Adamczuk, Lukasz Dziewit |
Abstract |
The draft genome of multidrug-resistant Aeromonas sp. ARM81 isolated from a wastewater treatment plant in Warsaw (Poland) was obtained. Sequence analysis revealed multiple genes conferring resistance to aminoglycosides, β-lactams or tetracycline. Three different β-lactamase genes were identified, including an extended-spectrum β-lactamase gene bla PER-1. The antibiotic susceptibility was experimentally tested. Genome sequencing also allowed us to investigate the plasmidome and transposable mobilome of ARM81. Four plasmids, of which two carry phenotypic modules (i.e., genes encoding a zinc transporter ZitB and a putative glucosyltransferase), and 28 putative transposase genes were identified. The mobility of three insertion sequences (isoforms of previously identified elements ISAs12, ISKpn9 and ISAs26) was confirmed using trap plasmids. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
India | 1 | 33% |
United Kingdom | 1 | 33% |
Unknown | 1 | 33% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 3 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 43 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Master | 11 | 26% |
Researcher | 8 | 19% |
Student > Bachelor | 3 | 7% |
Other | 2 | 5% |
Lecturer > Senior Lecturer | 2 | 5% |
Other | 5 | 12% |
Unknown | 12 | 28% |
Readers by discipline | Count | As % |
---|---|---|
Biochemistry, Genetics and Molecular Biology | 6 | 14% |
Agricultural and Biological Sciences | 6 | 14% |
Immunology and Microbiology | 3 | 7% |
Medicine and Dentistry | 3 | 7% |
Environmental Science | 2 | 5% |
Other | 3 | 7% |
Unknown | 20 | 47% |