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The Effects of Alteplase 3 to 6 Hours After Stroke in the EPITHET–DEFUSE Combined Dataset

Overview of attention for article published in Stroke, December 2012
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  • Above-average Attention Score compared to outputs of the same age and source (60th percentile)

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3 X users
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1 Facebook page

Citations

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66 Dimensions

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87 Mendeley
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Title
The Effects of Alteplase 3 to 6 Hours After Stroke in the EPITHET–DEFUSE Combined Dataset
Published in
Stroke, December 2012
DOI 10.1161/strokeaha.112.668301
Pubmed ID
Authors

Toshiyasu Ogata, Soren Christensen, Yoshinari Nagakane, Henry Ma, Bruce C.V. Campbell, Leonid Churilov, Maarten G. Lansberg, Matus Straka, Deidre A. De Silva, Michael Mlynash, Roland Bammer, Jean-Marc Olivot, Patricia M. Desmond, Gregory W. Albers, Stephen M. Davis, Geoffrey A. Donnan

Abstract

Two phase 2 studies of alteplase in acute ischemic stroke 3 to 6 hours after onset, Echoplanar Imaging Thrombolytic Evaluation Trial (EPITHET; a randomized, controlled, double-blinded trial), and Diffusion and Perfusion Imaging Evaluation for Understanding Stroke Evolution Study (DEFUSE; open-label, treatment only) using MR imaging-based outcomes have been conducted. We have pooled individual patient data from these to assess the response to alteplase. The primary hypothesis was that alteplase would significantly attenuate infarct growth compared with placebo in mismatch-selected patients using coregistration techniques.

X Demographics

X Demographics

The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 87 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Korea, Republic of 1 1%
Singapore 1 1%
Canada 1 1%
Unknown 84 97%

Demographic breakdown

Readers by professional status Count As %
Researcher 14 16%
Student > Ph. D. Student 11 13%
Student > Postgraduate 9 10%
Other 6 7%
Professor > Associate Professor 6 7%
Other 21 24%
Unknown 20 23%
Readers by discipline Count As %
Medicine and Dentistry 44 51%
Neuroscience 6 7%
Agricultural and Biological Sciences 3 3%
Engineering 3 3%
Nursing and Health Professions 2 2%
Other 8 9%
Unknown 21 24%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 14 January 2013.
All research outputs
#15,065,296
of 25,374,917 outputs
Outputs from Stroke
#9,155
of 12,372 outputs
Outputs of similar age
#170,620
of 288,545 outputs
Outputs of similar age from Stroke
#62
of 158 outputs
Altmetric has tracked 25,374,917 research outputs across all sources so far. This one is in the 40th percentile – i.e., 40% of other outputs scored the same or lower than it.
So far Altmetric has tracked 12,372 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 16.6. This one is in the 25th percentile – i.e., 25% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 288,545 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 40th percentile – i.e., 40% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 158 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 60% of its contemporaries.