Title |
Structural and Regulatory Genes Required to Make the Gas Dimethyl Sulfide in Bacteria
|
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Published in |
Science, February 2007
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DOI | 10.1126/science.1135370 |
Pubmed ID | |
Authors |
Jonathan D. Todd, Rachel Rogers, You Guo Li, Margaret Wexler, Philip L. Bond, Lei Sun, Andrew R. J. Curson, Gill Malin, Michael Steinke, Andrew W. B. Johnston |
Abstract |
Dimethyl sulfide (DMS) is a key compound in global sulfur and carbon cycles. DMS oxidation products cause cloud nucleation and may affect weather and climate. DMS is generated largely by bacterial catabolism of dimethylsulfoniopropionate (DMSP), a secondary metabolite made by marine algae. We demonstrate that the bacterial gene dddD is required for this process and that its transcription is induced by the DMSP substrate. Cloned dddD from the marine bacterium Marinomonas and from two bacterial strains that associate with higher plants, the N(2)-fixing symbiont Rhizobium NGR234 and the root-colonizing Burkholderia cepacia AMMD, conferred to Escherichia coli the ability to make DMS from DMSP. The inferred enzymatic mechanism for DMS liberation involves an initial step in which DMSP is modified by addition of acyl coenzyme A, rather than the immediate release of DMS by a DMSP lyase, the previously suggested mechanism. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 3 | 2% |
United Kingdom | 3 | 2% |
Canada | 2 | 1% |
Belgium | 2 | 1% |
Germany | 2 | 1% |
Netherlands | 1 | <1% |
Australia | 1 | <1% |
Malaysia | 1 | <1% |
India | 1 | <1% |
Other | 0 | 0% |
Unknown | 135 | 89% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 47 | 31% |
Researcher | 32 | 21% |
Student > Master | 12 | 8% |
Student > Doctoral Student | 8 | 5% |
Student > Bachelor | 8 | 5% |
Other | 21 | 14% |
Unknown | 23 | 15% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 56 | 37% |
Environmental Science | 32 | 21% |
Biochemistry, Genetics and Molecular Biology | 16 | 11% |
Earth and Planetary Sciences | 8 | 5% |
Chemistry | 4 | 3% |
Other | 11 | 7% |
Unknown | 24 | 16% |