| Title |
Does Therapeutic Repetitive Transcranial Magnetic Stimulation Cause Cognitive Enhancing Effects in Patients with Neuropsychiatric Conditions? A Systematic Review and Meta-Analysis of Randomised Controlled Trials
|
|---|---|
| Published in |
Neuropsychology Review, September 2016
|
| DOI | 10.1007/s11065-016-9325-1 |
| Pubmed ID | |
| Authors |
Donel M. Martin, Shawn M. McClintock, Jane Forster, Colleen K. Loo |
| Abstract |
Repetitive transcranial magnetic stimulation (rTMS) is increasingly used as a therapeutic intervention for neuropsychiatric illnesses and has demonstrated efficacy for treatment of major depression. However, an unresolved question is whether a course of rTMS treatment results in effects on cognitive functioning. In this systematic review and meta-analysis we aimed to quantitatively determine whether a course of rTMS has cognitive enhancing effects. We examined cognitive outcomes from randomised, sham-controlled studies conducted in patients with neuropsychiatric conditions where rTMS was administered to the dorsolateral prefrontal cortex (DLPFC) across repeated sessions, searched from PubMed/MEDLINE and other databases up until October 2015. Thirty studies met our inclusion criteria. Cognitive outcomes were pooled and examined across the following domains: Global cognitive function, executive function, attention, working memory, processing speed, visual memory, verbal memory and visuospatial ability. Active rTMS treatment was unassociated with generalised gains across the majority of domains of cognitive functioning examined. Secondary analyses revealed a moderate sized positive effect for improved working memory in a small number of studies in patients with schizophrenia (k = 3, g = 0.507, 95 % CI = [0.183-0.831], p < .01). Therapeutic rTMS when administered to the DLPFC in patients with neuropsychiatric conditions does not result in robust cognitive enhancing effects. |
X Demographics
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Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 169 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 169 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 29 | 17% |
| Student > Ph. D. Student | 24 | 14% |
| Student > Master | 24 | 14% |
| Student > Bachelor | 13 | 8% |
| Student > Postgraduate | 10 | 6% |
| Other | 21 | 12% |
| Unknown | 48 | 28% |
| Readers by discipline | Count | As % |
|---|---|---|
| Psychology | 37 | 22% |
| Medicine and Dentistry | 25 | 15% |
| Neuroscience | 23 | 14% |
| Nursing and Health Professions | 7 | 4% |
| Agricultural and Biological Sciences | 4 | 2% |
| Other | 17 | 10% |
| Unknown | 56 | 33% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 07 November 2016.
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#20,340,423
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#433
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Outputs of similar age from Neuropsychology Review
#9
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