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Spheroid culture as a tool for creating 3D complex tissues

Overview of attention for article published in Trends in Biotechnology, January 2013
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (92nd percentile)
  • Good Attention Score compared to outputs of the same age and source (74th percentile)

Mentioned by

twitter
5 X users
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10 patents
wikipedia
3 Wikipedia pages

Citations

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806 Dimensions

Readers on

mendeley
1434 Mendeley
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1 CiteULike
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Title
Spheroid culture as a tool for creating 3D complex tissues
Published in
Trends in Biotechnology, January 2013
DOI 10.1016/j.tibtech.2012.12.003
Pubmed ID
Authors

Eelco Fennema, Nicolas Rivron, Jeroen Rouwkema, Clemens van Blitterswijk, Jan de Boer

Abstract

3D cell culture methods confer a high degree of clinical and biological relevance to in vitro models. This is specifically the case with the spheroid culture, where a small aggregate of cells grows free of foreign materials. In spheroid cultures, cells secrete the extracellular matrix (ECM) in which they reside, and they can interact with cells from their original microenvironment. The value of spheroid cultures is increasing quickly due to novel microfabricated platforms amenable to high-throughput screening (HTS) and advances in cell culture. Here, we review new possibilities that combine the strengths of spheroid culture with new microenvironment fabrication methods that allow for the creation of large numbers of highly reproducible, complex tissues.

X Demographics

X Demographics

The data shown below were collected from the profiles of 5 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 1,434 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 7 <1%
Switzerland 4 <1%
United Kingdom 4 <1%
Germany 2 <1%
Canada 2 <1%
Czechia 1 <1%
Israel 1 <1%
New Zealand 1 <1%
Italy 1 <1%
Other 2 <1%
Unknown 1409 98%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 320 22%
Student > Master 235 16%
Researcher 204 14%
Student > Bachelor 174 12%
Student > Doctoral Student 63 4%
Other 158 11%
Unknown 280 20%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 280 20%
Agricultural and Biological Sciences 240 17%
Engineering 201 14%
Medicine and Dentistry 86 6%
Chemistry 73 5%
Other 214 15%
Unknown 340 24%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 16. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 06 December 2023.
All research outputs
#2,282,534
of 26,017,215 outputs
Outputs from Trends in Biotechnology
#335
of 2,877 outputs
Outputs of similar age
#21,820
of 297,755 outputs
Outputs of similar age from Trends in Biotechnology
#10
of 39 outputs
Altmetric has tracked 26,017,215 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 90th percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 2,877 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 9.7. This one has done well, scoring higher than 88% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 297,755 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 92% of its contemporaries.
We're also able to compare this research output to 39 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 74% of its contemporaries.