Title |
Fenugreek extract as an inducer of cellular death via autophagy in human T lymphoma Jurkat cells
|
---|---|
Published in |
BMC Complementary Medicine and Therapies, October 2012
|
DOI | 10.1186/1472-6882-12-202 |
Pubmed ID | |
Authors |
Nasser M Al-Daghri, Majed S Alokail, Khalid M Alkharfy, Abdul Khader Mohammed, Sherif H Abd-Alrahman, Sobhy M Yakout, Osama E Amer, Soundararajan Krishnaswamy |
Abstract |
Drugs used both in classical chemotherapy and the more recent targeted therapy do not have cancer cell specificity and, hence, cause severe systemic side effects. Tumors also develop resistance to such drugs due to heterogeneity of cell types and clonal selection. Several traditional dietary ingredients from plants, on the other hand, have been shown to act on multiple targets/pathways, and may overcome drug resistance. The dietary agents are safe and readily available. However, application of plant components for cancer treatment/prevention requires better understanding of anticancer functions and elucidation of their mechanisms of action. The current study focuses on the anticancer properties of fenugreek, a herb with proven anti-diabetic, antitumor and immune-stimulating functions. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 1 | 33% |
Unknown | 2 | 67% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 2 | 67% |
Practitioners (doctors, other healthcare professionals) | 1 | 33% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Portugal | 1 | 1% |
Unknown | 70 | 99% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 13 | 18% |
Student > Bachelor | 7 | 10% |
Researcher | 6 | 8% |
Student > Postgraduate | 6 | 8% |
Professor | 3 | 4% |
Other | 9 | 13% |
Unknown | 27 | 38% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 12 | 17% |
Biochemistry, Genetics and Molecular Biology | 11 | 15% |
Medicine and Dentistry | 10 | 14% |
Pharmacology, Toxicology and Pharmaceutical Science | 5 | 7% |
Chemistry | 2 | 3% |
Other | 6 | 8% |
Unknown | 25 | 35% |