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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Perturbation of cell cycle regulation triggers plant immune response via activation of disease resistance genes
|
|---|---|
| Published in |
Proceedings of the National Academy of Sciences of the United States of America, January 2013
|
| DOI | 10.1073/pnas.1217024110 |
| Pubmed ID | |
| Authors |
Zhilong Bao, Huijun Yang, Jian Hua |
| Abstract |
The Arabidopsis gene OSD1 (Omission of the Second Division) and its homolog UVI4 (UV-B-Insensitive 4) are negative regulators of anaphase-promoting complex/cyclosome (APC/C), a multisubunit ubiquitin E3 ligase that regulates the progression of cell cycles. Here we report the isolation of an activation tagging allele of OSD1 as an enhancer of a mutant of BON1 (BONZAI1), a negative regulator of plant immunity. Overexpression of OSD1 and UVI4 each leads to enhanced immunity to a bacterial pathogen, which is associated with increased expression of disease resistance (R) genes similar to the animal NOD1 receptor-like immune receptor genes. In addition, the reduction of function of one subunit of the APC complex APC10 exhibited a similar phenotype to that of overexpression of OSD1 or UVI4, indicating that altered APC function induces immune responses. Enhanced immune response induced by OSD1 overexpression is dependent on CYCB1;1, which is a degradation target of APC/C. It is also associated with up-regulation of R genes and is dependent on the R gene SNC1 (Suppressor of npr1-1, constitutive 1). Taken together, our findings reveal an unexpected link between cell cycle progression and plant immunity, suggesting that cell cycle misregulation could have an impact on expression of genes, including R genes, in plant immunity. |
X Demographics
The data shown below were collected from the profiles of 5 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 20% |
| Brazil | 1 | 20% |
| Chile | 1 | 20% |
| United Kingdom | 1 | 20% |
| Unknown | 1 | 20% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 4 | 80% |
| Scientists | 1 | 20% |
Mendeley readers
The data shown below were compiled from readership statistics for 106 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 2 | 2% |
| France | 1 | <1% |
| South Africa | 1 | <1% |
| Germany | 1 | <1% |
| Belgium | 1 | <1% |
| Taiwan | 1 | <1% |
| Croatia | 1 | <1% |
| Poland | 1 | <1% |
| Unknown | 97 | 92% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 31 | 29% |
| Student > Ph. D. Student | 18 | 17% |
| Student > Master | 13 | 12% |
| Student > Bachelor | 9 | 8% |
| Student > Doctoral Student | 8 | 8% |
| Other | 19 | 18% |
| Unknown | 8 | 8% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 78 | 74% |
| Biochemistry, Genetics and Molecular Biology | 15 | 14% |
| Philosophy | 1 | <1% |
| Environmental Science | 1 | <1% |
| Immunology and Microbiology | 1 | <1% |
| Other | 1 | <1% |
| Unknown | 9 | 8% |
Attention Score in Context
This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 10 October 2019.
All research outputs
#13,813,106
of 24,625,114 outputs
Outputs from Proceedings of the National Academy of Sciences of the United States of America
#86,094
of 101,438 outputs
Outputs of similar age
#159,398
of 290,021 outputs
Outputs of similar age from Proceedings of the National Academy of Sciences of the United States of America
#711
of 996 outputs
Altmetric has tracked 24,625,114 research outputs across all sources so far. This one is in the 43rd percentile – i.e., 43% of other outputs scored the same or lower than it.
So far Altmetric has tracked 101,438 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 38.8. This one is in the 15th percentile – i.e., 15% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 290,021 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 44th percentile – i.e., 44% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 996 others from the same source and published within six weeks on either side of this one. This one is in the 28th percentile – i.e., 28% of its contemporaries scored the same or lower than it.