Title |
D-Amino acid oxidase: Physiological role and applications
|
---|---|
Published in |
Biochemistry, January 2009
|
DOI | 10.1134/s0006297908130105 |
Pubmed ID | |
Authors |
S. V. Khoronenkova, V. I. Tishkov |
Abstract |
D-Amino acids play a key role in regulation of many processes in living cells. FAD-dependent D-amino acid oxidase (DAAO) is one of the most important enzymes responsible for maintenance proper level of D-amino acids. The most interesting and important data for regulation of the nervous system, hormone secretion, and other processes by D-amino acids as well as development of different diseases under changed DAAO activity are presented. The mechanism of regulation is complex and multi-parametric because the same enzyme simultaneously influences the level of different D-amino acids, which can result in opposing effects. Use of DAAO for diagnostic and therapeutic purposes is also considered. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Japan | 1 | 2% |
Russia | 1 | 2% |
Unknown | 62 | 97% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 13 | 20% |
Student > Master | 10 | 16% |
Student > Bachelor | 8 | 13% |
Student > Doctoral Student | 6 | 9% |
Researcher | 4 | 6% |
Other | 8 | 13% |
Unknown | 15 | 23% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 17 | 27% |
Biochemistry, Genetics and Molecular Biology | 10 | 16% |
Chemistry | 7 | 11% |
Medicine and Dentistry | 4 | 6% |
Pharmacology, Toxicology and Pharmaceutical Science | 2 | 3% |
Other | 9 | 14% |
Unknown | 15 | 23% |