| Title |
Physical declines occurring after hospital discharge in ARDS survivors: a 5-year longitudinal study
|
|---|---|
| Published in |
Intensive Care Medicine, September 2016
|
| DOI | 10.1007/s00134-016-4530-1 |
| Pubmed ID | |
| Authors |
Elizabeth R. Pfoh, Amy W. Wozniak, Elizabeth Colantuoni, Victor D. Dinglas, Pedro A. Mendez-Tellez, Carl Shanholtz, Nancy D. Ciesla, Peter J. Pronovost, Dale M. Needham |
| Abstract |
Survivors of acute respiratory distress syndrome (ARDS) are at high risk for new or ongoing physical declines after hospital discharge. The objective of our study was to evaluate the epidemiology of physical declines over 5-year follow-up and identify patients at risk for decline. This multi-site prospective cohort study evaluated ARDS survivors who completed a physical status assessment at 3 or 6 months post-discharge. Three measures were evaluated: muscle strength (Medical Resource Council sumscore); exercise capacity [6-min walk test (6MWT)]; physical functioning [36-Item Short Form Health Survey (SF-36 survey)]. Patients were defined as "declined" if a comparison of their current and prior score showed a decrease that was greater than the Reliable Change Index-or if the patient died. Risk factors [pre-ARDS baseline status, intensive care unit (ICU) illness severity, and other intensive care variables] were evaluated using longitudinal, generalized linear regression models for each measure. During the follow-up of 193 ARDS survivors (55 % male; median age 49 years), 166 (86 %) experienced decline in ≥1 physical measure (including death) and 133 (69 %) experienced a physical decline (excluding death). For all measures, age was a significant risk factor [odds ratios (OR) 1.34-1.69 per decade; p < 0.001]. Pre-ARDS comorbidity (Charlson Index) was independently associated with declines in strength and exercise capacity (OR 1.10 and 1.18, respectively; p < 0.02), and organ failure [maximum daily Sequential Organ Failure Assessment (SOFA) score in ICU] was associated with declines in strength (OR 1.06 per 1 point of SOFA score; p = 0.02). Over the follow-up period, the majority of ARDS survivors experienced a physical decline, with older age and pre-ICU comorbidity being important risk factors for this decline. |
X Demographics
The data shown below were collected from the profiles of 116 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 26 | 22% |
| Australia | 10 | 9% |
| United Kingdom | 9 | 8% |
| Mexico | 4 | 3% |
| Spain | 4 | 3% |
| Italy | 4 | 3% |
| Canada | 4 | 3% |
| Saudi Arabia | 3 | 3% |
| Belgium | 3 | 3% |
| Other | 7 | 6% |
| Unknown | 42 | 36% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 65 | 56% |
| Scientists | 27 | 23% |
| Practitioners (doctors, other healthcare professionals) | 17 | 15% |
| Science communicators (journalists, bloggers, editors) | 6 | 5% |
| Unknown | 1 | <1% |
Mendeley readers
The data shown below were compiled from readership statistics for 174 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 174 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 24 | 14% |
| Researcher | 22 | 13% |
| Other | 17 | 10% |
| Student > Doctoral Student | 14 | 8% |
| Student > Bachelor | 11 | 6% |
| Other | 42 | 24% |
| Unknown | 44 | 25% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 69 | 40% |
| Nursing and Health Professions | 25 | 14% |
| Agricultural and Biological Sciences | 5 | 3% |
| Social Sciences | 4 | 2% |
| Biochemistry, Genetics and Molecular Biology | 3 | 2% |
| Other | 12 | 7% |
| Unknown | 56 | 32% |
Attention Score in Context
This research output has an Altmetric Attention Score of 122. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 17 August 2023.
All research outputs
#343,285
of 25,377,790 outputs
Outputs from Intensive Care Medicine
#305
of 5,410 outputs
Outputs of similar age
#6,326
of 315,124 outputs
Outputs of similar age from Intensive Care Medicine
#3
of 125 outputs
Altmetric has tracked 25,377,790 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 98th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 5,410 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 29.6. This one has done particularly well, scoring higher than 94% of its peers.
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We're also able to compare this research output to 125 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 98% of its contemporaries.