Title |
Recommendations for treatment of hypothyroidism with levothyroxine and levotriiodothyronine: a 2016 position statement of the Italian Society of Endocrinology and the Italian Thyroid Association
|
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Published in |
Journal of Endocrinological Investigation, July 2016
|
DOI | 10.1007/s40618-016-0511-z |
Pubmed ID | |
Authors |
B. Biondi, L. Bartalena, L. Chiovato, A. Lenzi, S. Mariotti, F. Pacini, A. Pontecorvi, P. Vitti, F. Trimarchi |
Abstract |
Levothyroxine (L-T4) is recommended as lifelong replacement therapy for hypothyroidism. Recent clinical and experimental data support the addition of levotriiodothyronine (L-T3) treatment in some selected hypothyroid patients when their symptoms persist and their quality of life remains impaired despite adequate L-T4 monotherapy. An increase in L-T3 prescriptions has been recently observed in Italy due to availability of different L-T3 formulations, making it possible to clinicians to prescribe L-T3 alone or in combination with L-T4. The aim of the present position statement was to define the correct clinical indications, schedule, duration of treatment and contraindications of combined treatment with L-T4 and L-T3 in hypothyroid patients in an attempt to guide clinicians and to avoid potential adverse effects of overtreatment. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 45 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Bachelor | 7 | 16% |
Student > Master | 5 | 11% |
Student > Postgraduate | 5 | 11% |
Researcher | 4 | 9% |
Student > Ph. D. Student | 3 | 7% |
Other | 7 | 16% |
Unknown | 14 | 31% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 16 | 36% |
Psychology | 4 | 9% |
Nursing and Health Professions | 2 | 4% |
Neuroscience | 2 | 4% |
Pharmacology, Toxicology and Pharmaceutical Science | 2 | 4% |
Other | 5 | 11% |
Unknown | 14 | 31% |