| Title |
Electro-physiological changes in the brain induced by caffeine or glucose nasal spray
|
|---|---|
| Published in |
Psychopharmacology, September 2016
|
| DOI | 10.1007/s00213-016-4435-2 |
| Pubmed ID | |
| Authors |
K De Pauw, B Roelands, J Van Cutsem, U Marusic, T Torbeyns, R Meeusen |
| Abstract |
A direct link between the mouth cavity and the brain for glucose (GLUC) and caffeine (CAF) has been established. The aim of this study is to determine whether a direct link for both substrates also exist between the nasal cavity and the brain. Ten healthy male subjects (age 22 ± 1 years) performed three experimental trials, separated by at least 2 days. Each trial included a 20-s nasal spray (NAS) period in which solutions placebo (PLAC), GLUC, or CAF were provided in a double-blind, randomized order. During each trial, four cognitive Stroop tasks were performed: two familiarization trials and one pre- and one post-NAS trial. Reaction times and accuracy for different stimuli (neutral, NEUTR; congruent, CON; incongruent INCON) were determined. Electroencephalography was continuously measured throughout the trials. During the Stroop tasks pre- and post-NAS, the P300 was assessed and during NAS, source localization was performed using standardized low-resolution brain electromagnetic tomography (sLORETA). NAS activated the anterior cingulate cortex (ACC). CAF-NAS also increased θ and β activity in frontal cortices. Furthermore, GLUC-NAS increased the β activity within the insula. GLUC-NAS also increased the P300 amplitude with INCON (P = 0.046) and reduced P300 amplitude at F3-F4 and P300 latency at CP1-CP2-Cz with NEUTR (P = 0.001 and P = 0.016, respectively). The existence of nasal bitter and sweet taste receptors possibly induce these brain responses. Greater cognitive efficiency was observed with GLUC-NAS. CAF-NAS activated cingulate, insular, and sensorymotor cortices, whereas GLUC-NAS activated sensory, cingulate, and insular cortices. However, no effect on the Stroop task was found. |
X Demographics
The data shown below were collected from the profiles of 30 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 9 | 30% |
| United States | 4 | 13% |
| Guatemala | 1 | 3% |
| Mexico | 1 | 3% |
| Australia | 1 | 3% |
| Switzerland | 1 | 3% |
| Isle of Man | 1 | 3% |
| Belgium | 1 | 3% |
| France | 1 | 3% |
| Other | 0 | 0% |
| Unknown | 10 | 33% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 17 | 57% |
| Scientists | 10 | 33% |
| Practitioners (doctors, other healthcare professionals) | 3 | 10% |
Mendeley readers
The data shown below were compiled from readership statistics for 94 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 1% |
| Unknown | 93 | 99% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 13 | 14% |
| Student > Bachelor | 13 | 14% |
| Student > Ph. D. Student | 8 | 9% |
| Other | 5 | 5% |
| Researcher | 4 | 4% |
| Other | 14 | 15% |
| Unknown | 37 | 39% |
| Readers by discipline | Count | As % |
|---|---|---|
| Sports and Recreations | 13 | 14% |
| Psychology | 9 | 10% |
| Neuroscience | 8 | 9% |
| Medicine and Dentistry | 7 | 7% |
| Nursing and Health Professions | 6 | 6% |
| Other | 11 | 12% |
| Unknown | 40 | 43% |
Attention Score in Context
This research output has an Altmetric Attention Score of 18. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 19 January 2023.
All research outputs
#1,980,458
of 25,231,854 outputs
Outputs from Psychopharmacology
#474
of 5,642 outputs
Outputs of similar age
#33,609
of 329,624 outputs
Outputs of similar age from Psychopharmacology
#9
of 49 outputs
Altmetric has tracked 25,231,854 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 92nd percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
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We're also able to compare this research output to 49 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 83% of its contemporaries.