Title |
Inclusion of the benefits of enhanced cross-protection against cervical cancer and prevention of genital warts in the cost-effectiveness analysis of human papillomavirus vaccination in the Netherlands
|
---|---|
Published in |
BMC Infectious Diseases, February 2013
|
DOI | 10.1186/1471-2334-13-75 |
Pubmed ID | |
Authors |
Tjalke A Westra, Irina Stirbu-Wagner, Sara Dorsman, Eric D Tutuhatunewa, Edwin L de Vrij, Hans W Nijman, Toos Daemen, Jan C Wilschut, Maarten J Postma |
Abstract |
Infection with HPV 16 and 18, the major causative agents of cervical cancer, can be prevented through vaccination with a bivalent or quadrivalent vaccine. Both vaccines provide cross-protection against HPV-types not included in the vaccines. In particular, the bivalent vaccine provides additional protection against HPV 31, 33, and 45 and the quadrivalent vaccine against HPV31. The quadrivalent vaccine additionally protects against low-risk HPV type 6 and 11, responsible for most cases of genital warts. In this study, we made an analytical comparison of the two vaccines in terms of cost-effectiveness including the additional benefits of cross-protection and protection against genital warts in comparison with a screening-only strategy. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
South Africa | 1 | 20% |
Netherlands | 1 | 20% |
United States | 1 | 20% |
Unknown | 2 | 40% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 3 | 60% |
Scientists | 1 | 20% |
Practitioners (doctors, other healthcare professionals) | 1 | 20% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Spain | 1 | <1% |
United States | 1 | <1% |
Netherlands | 1 | <1% |
Brazil | 1 | <1% |
Unknown | 106 | 96% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Master | 25 | 23% |
Researcher | 16 | 15% |
Student > Postgraduate | 8 | 7% |
Student > Doctoral Student | 8 | 7% |
Student > Ph. D. Student | 8 | 7% |
Other | 17 | 15% |
Unknown | 28 | 25% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 31 | 28% |
Pharmacology, Toxicology and Pharmaceutical Science | 10 | 9% |
Agricultural and Biological Sciences | 6 | 5% |
Economics, Econometrics and Finance | 6 | 5% |
Nursing and Health Professions | 5 | 5% |
Other | 19 | 17% |
Unknown | 33 | 30% |