Title |
Bile acids in treatment of ocular disease
|
---|---|
Published in |
Journal of Ocular Biology, Diseases, and Informatics, August 2009
|
DOI | 10.1007/s12177-009-9030-x |
Pubmed ID | |
Authors |
Jeffrey H. Boatright, John M. Nickerson, Anisha G. Moring, Machelle T. Pardue |
Abstract |
Bear bile has been included in Asian pharmacopeias for thousands of years in treatment of several diseases, ranging from sore throat to hemorrhoids. The hydrophilic bile acids tauroursodeoxycholic acid (TUDCA) and ursodeoxycholic acid (UDCA) are the major bile acids of bear bile. Both of these are available as synthetic formulations and are approved by the health administrations of several countries for treatment of cirrhosis and gallstones. This review briefly covers the use of bear bile in Traditional Chinese Medicine, bile acid physiology, approved use of UDCA and TUDCA in Western medicine, and recent research exploring their neuroprotective properties, including in models of ocular disease. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 1 | 100% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Scientists | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 1 | 1% |
Portugal | 1 | 1% |
Korea, Republic of | 1 | 1% |
Unknown | 64 | 96% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 10 | 15% |
Student > Ph. D. Student | 7 | 10% |
Student > Master | 7 | 10% |
Student > Postgraduate | 6 | 9% |
Other | 5 | 7% |
Other | 13 | 19% |
Unknown | 19 | 28% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 16 | 24% |
Agricultural and Biological Sciences | 11 | 16% |
Biochemistry, Genetics and Molecular Biology | 7 | 10% |
Pharmacology, Toxicology and Pharmaceutical Science | 4 | 6% |
Neuroscience | 3 | 4% |
Other | 6 | 9% |
Unknown | 20 | 30% |