| Title |
Use of Vitex agnus-castus in migrainous women with premenstrual syndrome: an open-label clinical observation
|
|---|---|
| Published in |
Acta Neurologica Belgica, July 2012
|
| DOI | 10.1007/s13760-012-0111-4 |
| Pubmed ID | |
| Authors |
Anna Ambrosini, Cherubino Di Lorenzo, Gianluca Coppola, Francesco Pierelli |
| Abstract |
Premenstrual syndrome (PMS) affects most women during their reproductive life. Headache is regarded as a typical symptom of PMS and, close to menses, migrainous women could experience their worst migraine attacks. Vitex agnus-castus (VAC) is a phytopharmaceutical compound, considered worldwide to be a valid tool to treat PMS. Aim of this study is to explore if headache is ameliorate in migrainous women treated with VAC for PMS by an open-label clinical observation. Migrainous women with PMS were enrolled in the study and advised to assume a treatment with VAC (40 mg/day) for PMS for a 3-month period. Effects both on PMS and headache were assessed. Out of 107 women, 100 completed the 3-month treatment for PMS. Out of them, 66 women reported a dramatic reduction of PMS symptoms, 26 a mild reduction, and 8 no effect. Concerning migraine, 42 % of patients experienced a reduction higher than 50 % in frequency of monthly attacks, and 57 % of patients experienced a reduction higher than 50 % in monthly days with headache. No patients reported remarkable side effects. Pending a placebo-controlled trial to confirm our results, we observed that the use of VAC in migrainous women affected by PMS resulted to be safe and well tolerated, and may positively influence the frequency and duration of migraine attacks. |
X Demographics
The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 2 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 2 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 80 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Australia | 2 | 3% |
| Russia | 1 | 1% |
| Unknown | 77 | 96% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 29 | 36% |
| Other | 9 | 11% |
| Researcher | 9 | 11% |
| Student > Master | 4 | 5% |
| Student > Doctoral Student | 3 | 4% |
| Other | 12 | 15% |
| Unknown | 14 | 18% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 32 | 40% |
| Agricultural and Biological Sciences | 11 | 14% |
| Biochemistry, Genetics and Molecular Biology | 3 | 4% |
| Social Sciences | 3 | 4% |
| Chemistry | 3 | 4% |
| Other | 11 | 14% |
| Unknown | 17 | 21% |
Attention Score in Context
This research output has an Altmetric Attention Score of 32. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 12 November 2020.
All research outputs
#1,141,086
of 24,217,893 outputs
Outputs from Acta Neurologica Belgica
#21
of 809 outputs
Outputs of similar age
#6,210
of 167,017 outputs
Outputs of similar age from Acta Neurologica Belgica
#1
of 5 outputs
Altmetric has tracked 24,217,893 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 95th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 809 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.9. This one has done particularly well, scoring higher than 97% of its peers.
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