| Title |
Genome-wide analysis validates aberrant methylation in fragile X syndrome is specific to the FMR1locus
|
|---|---|
| Published in |
BMC Medical Genomics, January 2013
|
| DOI | 10.1186/1471-2350-14-18 |
| Pubmed ID | |
| Authors |
Reid S Alisch, Tao Wang, Pankaj Chopra, Jeannie Visootsak, Karen N Conneely, Stephen T Warren |
| Abstract |
Fragile X syndrome (FXS) is a common form of inherited intellectual disability caused by an expansion of CGG repeats located in the 5' untranslated region (UTR) of the FMR1 gene, which leads to hypermethylation and silencing of this locus. Although a dramatic increase in DNA methylation of the FMR1 full mutation allele is well documented, the extent to which these changes affect DNA methylation throughout the rest of the genome has gone unexplored. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| France | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 88 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 2 | 2% |
| United Kingdom | 1 | 1% |
| Unknown | 85 | 97% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 19 | 22% |
| Student > Bachelor | 13 | 15% |
| Researcher | 12 | 14% |
| Other | 9 | 10% |
| Student > Master | 9 | 10% |
| Other | 15 | 17% |
| Unknown | 11 | 13% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 26 | 30% |
| Biochemistry, Genetics and Molecular Biology | 21 | 24% |
| Neuroscience | 10 | 11% |
| Medicine and Dentistry | 9 | 10% |
| Chemistry | 4 | 5% |
| Other | 6 | 7% |
| Unknown | 12 | 14% |
Attention Score in Context
This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 31 December 2020.
All research outputs
#7,356,343
of 25,374,647 outputs
Outputs from BMC Medical Genomics
#501
of 2,444 outputs
Outputs of similar age
#73,502
of 290,753 outputs
Outputs of similar age from BMC Medical Genomics
#6
of 31 outputs
Altmetric has tracked 25,374,647 research outputs across all sources so far. This one has received more attention than most of these and is in the 69th percentile.
So far Altmetric has tracked 2,444 research outputs from this source. They receive a mean Attention Score of 4.4. This one has done well, scoring higher than 78% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 290,753 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 73% of its contemporaries.
We're also able to compare this research output to 31 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 80% of its contemporaries.