| Title |
Coffee consumption and risk of all-cause, cardiovascular, and cancer mortality in smokers and non-smokers: a dose-response meta-analysis
|
|---|---|
| Published in |
European Journal of Epidemiology, October 2016
|
| DOI | 10.1007/s10654-016-0202-2 |
| Pubmed ID | |
| Authors |
Giuseppe Grosso, Agnieszka Micek, Justyna Godos, Salvatore Sciacca, Andrzej Pajak, Miguel A. Martínez-González, Edward L. Giovannucci, Fabio Galvano |
| Abstract |
Coffee consumption has been associated with several benefits toward human health. However, its association with mortality risk has yielded contrasting results, including a non-linear relation to all-cause and cardiovascular disease (CVD) mortality and no association with cancer mortality. As smoking habits may affect the association between coffee and health outcomes, the aim of the present study was to update the latest dose-response meta-analysis of prospective cohort studies on the association between coffee consumption and mortality risk and conduct stratified analyses by smoking status and other potential confounders. A systematic search was conducted in electronic databases to identify relevant studies, risk estimates were retrieved from the studies, and dose-response analysis was modeled by using restricted cubic splines. A total of 31 studies comprising 1610,543 individuals and 183,991 cases of all-cause, 34,574 of CVD, and 40,991 of cancer deaths were selected. Analysis showed decreased all-cause [relative risk (RR) = 0.86, 95 % confidence interval (CI) = 0.82, 0.89)] and CVD mortality risk (RR = 0.85, 95 % CI = 0.77, 0.93) for consumption of up to 4 cups/day of coffee, while higher intakes were associated with no further lower risk. When analyses were restricted only to non-smokers, a linear decreased risk of all-cause (RR = 0.94, 95 % CI = 0.93, 0.96), CVD (RR = 0.94, 95 % CI = 0.91, 0.97), and cancer mortality (RR = 0.98, 95 % CI = 0.96, 1.00) for 1 cup/day increase was found. The search for other potential confounders, including dose-response analyses in subgroups by gender, geographical area, year of publication, and type of coffee, showed no relevant differences between strata. In conclusion, coffee consumption is associated with decreased risk of mortality from all-cause, CVD, and cancer; however, smoking modifies the observed risk when studying the role of coffee on human health. |
X Demographics
The data shown below were collected from the profiles of 53 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Spain | 16 | 30% |
| Netherlands | 2 | 4% |
| Venezuela, Bolivarian Republic of | 1 | 2% |
| Mexico | 1 | 2% |
| Ecuador | 1 | 2% |
| Canada | 1 | 2% |
| Australia | 1 | 2% |
| Norway | 1 | 2% |
| Italy | 1 | 2% |
| Other | 2 | 4% |
| Unknown | 26 | 49% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 40 | 75% |
| Practitioners (doctors, other healthcare professionals) | 7 | 13% |
| Scientists | 5 | 9% |
| Science communicators (journalists, bloggers, editors) | 1 | 2% |
Mendeley readers
The data shown below were compiled from readership statistics for 160 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Spain | 1 | <1% |
| Unknown | 159 | 99% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 29 | 18% |
| Student > Master | 18 | 11% |
| Researcher | 13 | 8% |
| Student > Postgraduate | 13 | 8% |
| Other | 11 | 7% |
| Other | 34 | 21% |
| Unknown | 42 | 26% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 51 | 32% |
| Nursing and Health Professions | 12 | 8% |
| Agricultural and Biological Sciences | 11 | 7% |
| Biochemistry, Genetics and Molecular Biology | 8 | 5% |
| Pharmacology, Toxicology and Pharmaceutical Science | 5 | 3% |
| Other | 18 | 11% |
| Unknown | 55 | 34% |
Attention Score in Context
This research output has an Altmetric Attention Score of 103. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 10 December 2023.
All research outputs
#414,196
of 25,655,374 outputs
Outputs from European Journal of Epidemiology
#74
of 1,815 outputs
Outputs of similar age
#7,936
of 330,048 outputs
Outputs of similar age from European Journal of Epidemiology
#1
of 15 outputs
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