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Increased Smad signaling and reduced MRF expression in skeletal muscle from obese subjects

Overview of attention for article published in Obesity, April 2013
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Title
Increased Smad signaling and reduced MRF expression in skeletal muscle from obese subjects
Published in
Obesity, April 2013
DOI 10.1002/oby.20070
Pubmed ID
Authors

Rani Watts, Andrew J. McAinch, John B. Dixon, Paul E. O'Brien, David Cameron‐Smith

Abstract

The molecular mechanisms underpinning the loss of skeletal muscle mass and strength associated with insulin resistance remain to be extensively investigated. There is mounting recognition that certain ligands of the transforming growth factor (TGF)-β family are upregulated in insulin resistant states, including obesity. This study analyses the expression of potent ligands of this family, TGF-β1 and myostatin (MSTN) and downstream components of the canonical TGF-β family signaling pathway (Smads) in skeletal muscle from lean and insulin resistant obese subjects.

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X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 40 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 40 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 8 20%
Student > Master 5 13%
Student > Doctoral Student 4 10%
Student > Ph. D. Student 4 10%
Student > Postgraduate 4 10%
Other 9 23%
Unknown 6 15%
Readers by discipline Count As %
Agricultural and Biological Sciences 15 38%
Biochemistry, Genetics and Molecular Biology 10 25%
Medicine and Dentistry 4 10%
Nursing and Health Professions 3 8%
Sports and Recreations 2 5%
Other 0 0%
Unknown 6 15%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 17 February 2013.
All research outputs
#20,039,697
of 24,629,540 outputs
Outputs from Obesity
#3,725
of 4,242 outputs
Outputs of similar age
#136,301
of 178,813 outputs
Outputs of similar age from Obesity
#142
of 180 outputs
Altmetric has tracked 24,629,540 research outputs across all sources so far. This one is in the 10th percentile – i.e., 10% of other outputs scored the same or lower than it.
So far Altmetric has tracked 4,242 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 37.6. This one is in the 5th percentile – i.e., 5% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 178,813 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 12th percentile – i.e., 12% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 180 others from the same source and published within six weeks on either side of this one. This one is in the 10th percentile – i.e., 10% of its contemporaries scored the same or lower than it.