| Title |
Effects of prebiotics on immune system and cytokine expression
|
|---|---|
| Published in |
Medical Microbiology and Immunology, October 2016
|
| DOI | 10.1007/s00430-016-0481-y |
| Pubmed ID | |
| Authors |
Parisa Shokryazdan, Mohammad Faseleh Jahromi, Bahman Navidshad, Juan Boo Liang |
| Abstract |
Nowadays, use of prebiotics as feed and food additives has received increasing interest because of the beneficial effects of prebiotics on the health of animals and humans. One of the beneficial effects of prebiotics is stimulation of immune system, which can be direct or indirect through increasing population of beneficial microbes or probiotics, especially lactic acid bacteria and bifidobacteria, in the gut. An important mechanism of action of probiotics and prebiotics, by which they can affect the immune system, is changing the expression of cytokines. The present review tried to summarize the findings of studies that investigated the effects of prebiotics on immune system with focusing on their effects on cytokine expression. Generally, most of reviewed studies indicated beneficial effects for prebiotics in terms of improving immune system, by increasing the expression of anti-inflammatory cytokines, while reducing the expressions of proinflammatory cytokines. However, most of studies mainly considered the indirect effects of prebiotics on the immune system (through changing the composition and population of gut microbiota), and their direct effects still need to be further studied using prebiotics with different degree of polymerization in different hosts. |
X Demographics
The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 2 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 2 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 240 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 1 | <1% |
| Spain | 1 | <1% |
| Germany | 1 | <1% |
| Unknown | 237 | 99% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 33 | 14% |
| Student > Master | 32 | 13% |
| Student > Ph. D. Student | 31 | 13% |
| Researcher | 27 | 11% |
| Student > Postgraduate | 15 | 6% |
| Other | 40 | 17% |
| Unknown | 62 | 26% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 42 | 18% |
| Biochemistry, Genetics and Molecular Biology | 29 | 12% |
| Medicine and Dentistry | 24 | 10% |
| Immunology and Microbiology | 17 | 7% |
| Nursing and Health Professions | 9 | 4% |
| Other | 39 | 16% |
| Unknown | 80 | 33% |
Attention Score in Context
This research output has an Altmetric Attention Score of 202. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 03 December 2022.
All research outputs
#188,919
of 24,932,434 outputs
Outputs from Medical Microbiology and Immunology
#3
of 644 outputs
Outputs of similar age
#3,727
of 326,687 outputs
Outputs of similar age from Medical Microbiology and Immunology
#2
of 9 outputs
Altmetric has tracked 24,932,434 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 99th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 644 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.6. This one has done particularly well, scoring higher than 99% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 326,687 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 98% of its contemporaries.
We're also able to compare this research output to 9 others from the same source and published within six weeks on either side of this one. This one has scored higher than 7 of them.