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Biological Reactive Intermediates VI

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Cover of 'Biological Reactive Intermediates VI'

Table of Contents

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    Book Overview
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    Chapter 1 Biological Reactive Intermediates and Mechanisms of Cell Death
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    Chapter 2 Structure Activity Relationships for the Chemical Behaviour and Toxicity of Electrophilic Quinones/Quinone Methides
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    Chapter 3 Use of Structure-Activity Relationships for Probing Biochemical Mechanisms: Glutathione Transferase Zeta Conjugation of Haloacids
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    Chapter 4 Structure Toxicity Relationships - How Useful Are They in Predicting Toxicities of New Drugs?
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    Chapter 5 Biological Reactive Intermediates in Drug Discovery and Development
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    Chapter 6 Bioactivation of Toxicants by Cytochrome P450-Mediated Dehydrogenation Mechanisms
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    Chapter 7 New Aspects of DNA Adduct Formation by the Carcinogens Crotonaldehyde and Acetaldehyde
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    Chapter 8 Mechanisms of Ovotoxicity Induced by Environmental Chemicals: 4-Vinylcyclohexene Diepoxide as a Model Chemical
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    Chapter 9 Mutagenicity and Carcinogenicity of Biological Reactive Intermediate’s Derived from a “Non-Genotoxic” Carcinogen
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    Chapter 10 Reactive Metabolites of 1,3-Butadiene: DNA and Hemoglobin Adduct Formation and Potential Roles in Carcinogenicity
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    Chapter 11 Chemistry and Biological Activity of Novel Selenium-Containing Compounds
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    Chapter 12 Formation and Fate of Reactive Intermediates of Haloalkanes, Haloalkenes, and α-Haloacids
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    Chapter 13 Human Epoxide Hydrolase is the Target of Germander Autoantibodies on the Surface of Human Hepatocytes: Enzymatic Implications
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    Chapter 14 Structural Characterisation Of the Main Epichlorohydringuanosine Adducts
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    Chapter 15 Adducts of the Chloroform Metabolite Phosgene
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    Chapter 16 Oxygenation of Arachidonic Acid by Cyclooxygenases Generates Reactive Intermediates That Form Adducts with Proteins
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    Chapter 17 Use of Isotopes and LC-MS-ESI-TOF for Mechanistic Studies of Tienilic Acid Metabolic Activation
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    Chapter 18 Inhibition by Ticlopidine and Its Derivatives of Human Liver Cytochrome P450. Mechanism-Based Inactivation of CYP 2C19 by Ticlopidine
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    Chapter 19 Microperoxidase 8 (MP8) as a Convenient Model for Hemoproteins: Formation and Characterisation of New Iron(II)-Nitrosoalkane Complexes of Biological Relevance
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    Chapter 20 Hemoglobin Adducts in Rats Chronically Exposed to Room-Aged Cigarette Sidestream Smoke and Diesel Engine Exhaust
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    Chapter 21 DNA Microarray Reveals Increased Expression of Thioredoxin Peroxidase in Thioredoxin-1 Transfected Cells and Its Functional Consequences
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    Chapter 22 Reactive Nitrogen Species and Proteins: Biological Significance and Clinical Relevance
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    Chapter 23 Bicarbonate Enhances Nitration and Oxidation Reactions in Biological Systems—Role of Reactive Oxygen and Nitrogen Species
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    Chapter 24 Nitric Oxide and Peroxynitrite in Ozone-Induced Lung Injury
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    Chapter 25 Antioxidant Reactions of Green Tea Catechins and Soy Isoflavones
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    Chapter 26 Reactive Oxygen Species Analysis in Gastritis Patients and P53 Methylation Analysis in Gastric Tumor Cell Line Ags Infected by Helicobacter Pylori
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    Chapter 27 Biological Reactive Intermediates that Mediate Chromium (VI) Toxicity
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    Chapter 28 Involvement of Peroxynitrite on the Early Loss of P450 in Short-Term Hepatocyte Cultures
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    Chapter 29 Lack of Correlation Between CYP2A6 Genotype and Smoking Habits
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    Chapter 30 Free Radical Lipid Peroxidation and Monooxygenase Activity in Experimental Influenza Virus Infection after Treatment with Rimantadine
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    Chapter 31 Oxidative Stress and the Structure/Activity Relationships of Ergopeptide Alkaloids
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    Chapter 32 Multiple Oxidative Stress Parameters are Modulated in Vitro by Oxygenated Polycyclic Aromatic Hydrocarbons Identified in River Sediments
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    Chapter 33 1,N 6-Etheno-2’-Deoxyadenosine Adducts from Trans, Trans-2,4-Decadienal and Trans-2-Octenal
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    Chapter 34 Hydrogen Peroxide Supports Hepatocyte P450 Catalysed Xenobiotic/Drug Metabolic Activation to form Cytotoxic Reactive Intermediates
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    Chapter 35 NAD(P)H:Quinone Oxidoreductase (NQO1) Protects Astroglial Cells Against L-Dopa Toxicity
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    Chapter 36 GSH-Dependent Redox Regulation and Antioxidant Enzymes in the Formation of Resistance to Doxorubicin in K562 Human Erythroleukemia Cells
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    Chapter 37 Opposite Effects of Oxidative Stress on Endothelial Cell Lines (ECV 304 and Eahy 926) Interaction With Extracellular Matrix
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    Chapter 38 Hepatocyte Lysis Induced by Environmental Metal Toxins May Involve Apoptotic Death Signals Initiated by Mitochondrial Injury
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    Chapter 39 Quantification of F-Ring and D-/E-Ring Isoprostanes and Neuroprostanes in Alzheimer’s Disease
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    Chapter 40 Preventive Effect of Vitamin E on the Processes of Free Radical Lipid Peroxidation and Monooxygenase Enzyme Activity in Experimental Influenza Virus Infection
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    Chapter 41 Lysosomal Oxidative Stress Cytotoxicity Induced by Nitrofurantoin Redox Cycling in Hepatocytes
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    Chapter 42 Scavenging and Antioxidant Effects of Estrogen Derivatives in Cholesterol-Fed Rabbits
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    Chapter 43 Inhibition of Oxidative Damage of Red Blood Cells and Liver Tissue by Genistein-8C-Glucoside
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    Chapter 44 Effects of Several Wine Polyphenols on Lipid Peroxidation and Oxygen Activation in Rat Liver Microsomes
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    Chapter 45 Chromosome Damage from Biological Reactive Intermediates of Benzene and 1,3-Butadiene in Leukemia
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    Chapter 46 The Antitumor Agent Ecteinascidin 743: Characterization of Its Covalent Dna Adducts and Chemical Stability
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    Chapter 47 Design of DNA Damaging Agents that Hijack Transcription Factors and Block DNA Repair
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    Chapter 48 The Potential Role of Topoisomerase II Inhibition in Hydroquinone-Induced Alterations in the Maturation of Mouse Myeloblasts
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    Chapter 49 Design and Characterization of a Novel « Family-Shuffling » Technology Adapted to Membrane Enzyme: Application to P450s Involved in Xenobiotic Metabolism
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    Chapter 50 One-Electron Reduction of Quinones by the Neuronal Nitric-Oxide Synthase Reductase Domain
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    Chapter 51 Purification, Biochemical Characterization and Comparative Enzyme Kinetics of Recombinant Human CYP2D6 1 and CYP2D6 2 Variants
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    Chapter 52 Inhibitory Effects of Roquefortine on Hepatic Cytochromes P450
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    Chapter 53 Association of Cytochromes P450 1A2 and 2B4: are the Interactions between Different p450 Species Involved in the Control of the Monooxygenase Activity and Coupling?
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    Chapter 54 Inactivation of Polymorphic Variants of Human Glutathione Transferase Zeta (hGSTZ1-1) by Maleylacetone and Fumarylacetone
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    Chapter 55 Structure-Activity Relationships of Cyclotetrapeptides: Interaction of Tentoxin Derivatives with Three Membrane Proteins
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    Chapter 56 Triazolam Substrate Inhibition
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    Chapter 57 Effect of the Microsomal System on Quinone Redox Cycling, Oxygen Activation, and Lipid Peroxidation
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    Chapter 58 Reaction of Nucleic Acids with Triformylmethane; A Novel Dna-Modifying Agent
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    Chapter 59 Are Blood-brain Interfaces Efficient in Protecting the Brain from Reactive Molecules ?
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    Chapter 60 The Roles of P-Glycoprotein and MRP1 in the Blood-Brain and Blood-Cerebrospinal Fluid Barriers
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    Chapter 61 Are Dopamine, Norepinephrine, and Serotonin Precursors of Biologically Reactive Intermediates Involved in the Pathogenesis of Neurodegenerative Brain Disorders?
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    Chapter 62 Serotonergic Neurotoxicity of Methylenedioxyamphetamine and Methylenedioxymetamphetamine
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    Chapter 63 Caspase Cascades in Chemically-Induced Apoptosis
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    Chapter 64 Spermatogenesis by Sisyphus: Proliferating Stem Germ Cells Fail to Repopulate the Testis after ‘Irreversible’ Injury
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    Chapter 65 The Interaction of 1,4-Benzoquinone, a Bioreactive Intermediate of Benzene, with Three Proteins Essential for Differentiation/ Maturation of the Mouse Myeloid Stem Cell
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    Chapter 66 Hematopoietic Stem and Progenitor Cells as Targets for Biological Reactive Intermediates
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    Chapter 67 Metabolism of 4-(Methylnitrosamino)-1-(3-Pyridyl)-1-Butanone (Nnk) in A/J Mouse Lung And Effect of Cigarette Smoke Exposure on in Vivo Metabolism to Biological Reactive Intermediates
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    Chapter 68 Pharmacokinetics of Benzene Following an Oral or Intradermal Dose in FVB and Tg.AC Mice
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    Chapter 69 Metabolism of the Food Mutagen 2-Amino-3,8-Dimethylimidazo[4,5-f]Quinoxaline in Human Hepatocytes
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    Chapter 70 Preventive Effect of Selenium on T-2 Toxin Membrane Toxicity
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    Chapter 71 Modulation Influence of p-Chloromercuribenzoate on Plasma Membrane Na+-Ca2+Exchanger of the Secretory Cells of Chironomus Larvae Salivary Gland
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    Chapter 72 Tobacco Toxicology Revisited
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    Chapter 74 Mitochondrial-Derived Oxidants and Quartz Activation of Chemokine Gene Expression
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    Chapter 75 Quinoids as Reactive Intermediates in Estrogen Carcinogenesis
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    Chapter 76 Assessing Underlying Mechanisms of Quinoid-Induced Hematopoietic Cell Toxicity
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    Chapter 77 Structure of the Malondialdehyde Deoxyguanosine Adduct M1G When Placed Opposite a Two-Base Deletion in the (CpG)3 Frameshift Hotspot of the Salmonella Typhimurium hisd3052 Gene
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    Chapter 78 A Sensitive Procedure for the Determination of Protein Bound 3,4-Dihydroxyphenyl-Alanine as a Marker for Posttranslational Protein Hydroxylation in Human Frontal Cortex, Liver, and Red Blood Cells
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    Chapter 79 Reactive Metabolite Screen for Reducing Candidate Attrition in Drug Discovery
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    Chapter 80 Metabolism of R,S Enantiomers of 3-Phenylamino-1,2-Propanediol, a Compound Associated with the Toxic Oil Syndrome, in C57BL/6- and A/J-Strain Mice
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    Chapter 81 Cytochrome P450-Catalysed Irreversible Binding Examined in Precision-Cut Adrenal Slice Culture
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    Chapter 82 Elevation of Glutathione Levels by Coffee Components and Its Potential Mechanisms
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    Chapter 83 Inhibition of Carcinogenesis and Toxicity by Dietary Constituents
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    Chapter 84 Modelling the Responses to Biological Reactive Intermediates
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    Chapter 85 Interindividual Differences in Response to Chemoprotection Against Aflatoxin-Induced Hepatocarcinogenesis: Implications for Human Biotransformation Enzyme Polymorphisms
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    Chapter 86 Sequestration of Biological Reactive Intermediates by Trapping as Covalent Enzyme-Intermediate Complex
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    Chapter 87 Chemoprotection and Interindividual Differences in Response to Biological Reactive Intermediates
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    Chapter 88 Oxidative Stress, Glucose-6-Phosphate Dehydrogenase and the Red Cell
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    Chapter 89 Hepatocarcinogenesis in the Context of Strain Differences in Energy Metabolism Between Inbred Strains of Mice (C57BL/6J and C3H/He)
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    Chapter 90 Characterization of hOGG1 Promoter Structure, Expression During Cell Cycle and Overexpression in Mammalian Cells
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    Chapter 91 hOGG1 Gene Alterations in Human Clear Cell Carcinomas of The Kidney: Effect of Single Mutations in hOGG1 Gene on Substrate Specificity of The hOgg1 Protein
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    Chapter 92 Proinflammatory Cytokines mRNA Expression in Dependence of Suppressive Epitope of Retroviral Transmembrane p15E Peptide Activation at Multiple Sclerosis Patients
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    Chapter 93 Determination of Nucleotide Excision Repair Capacity of Liver Cells in Vivo and in Vitro by a Cell-Free Assay
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    Chapter 94 Dietary Induction of Phase II Enzymes: A Promising Strategy for Protection Against DNA-Reactive Intermediates in Man?
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    Chapter 95 Concurrent Flavin-Containing Monooxygenase Down Regulation and Cytochrome P450 Induction by Dietary Indoles in the Rat: Implication for Drug-Drug Interactions
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    Chapter 96 Reactive Intermediates in Biological Systems: What Have We Learned and Where Are We Going?
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    Chapter 97 The Role of Toxicological Science in Risk Assessment and Risk Management
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    Chapter 98 Covalent Binding of Chemical Residues: Health Impact
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    Chapter 99 Identification of Hepatic Protein Targets of the Reactive Metabolites of the Non-hepatotoxic Regioisomer of Acetaminophen, 3’-Hydroxyacetanilide, in the Mouse in Vivo Using Two-Dimensional Gel Electrophoresis and Mass Spectrometry
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    Chapter 100 Exocyclic DNA Adducts as Secondary Markers for Oxidative Stress: Applications in Human Cancer Etiology and Risk Assessment
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    Chapter 101 Dose Dependent Induction of DNA Adducts, Gene Mutations, and Cell Proliferation by the Antiandrogenic Drug Cyproterone Acetate in Rat Liver
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    Chapter 102 Dose-Dependent Differences in the Profile of Mutations Induced by Carcinogenic (R,S,S,R) Bay-and Fjord-Region Diol Epoxides of Polycyclic Aromatic Hydrocarbons
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    Chapter 103 Nucleic Acid Microarray Technology For Toxicology: Promise And Practicalities
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    Chapter 104 Use of Covalent Binding in Risk Assessment
Overall attention for this book and its chapters
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Mentioned by

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Title
Biological Reactive Intermediates VI
Published by
Advances in experimental medicine and biology, January 2001
DOI 10.1007/978-1-4615-0667-6
ISBNs
978-1-4613-5185-6, 978-1-4615-0667-6
Editors

Patrick M. Dansette, Robert Snyder, Marcel Delaforge, G. Gordon Gibson, Helmut Greim, David J. Jollow, Terrence J. Monks, I. Glenn Sipes

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 9 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Poland 1 11%
Unknown 8 89%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 1 11%
Student > Bachelor 1 11%
Researcher 1 11%
Unknown 6 67%
Readers by discipline Count As %
Agricultural and Biological Sciences 2 22%
Biochemistry, Genetics and Molecular Biology 1 11%
Unknown 6 67%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 14 September 2021.
All research outputs
#7,488,524
of 22,890,496 outputs
Outputs from Advances in experimental medicine and biology
#1,230
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Outputs of similar age
#26,496
of 114,464 outputs
Outputs of similar age from Advances in experimental medicine and biology
#5
of 19 outputs
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So far Altmetric has tracked 4,952 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.1. This one has gotten more attention than average, scoring higher than 65% of its peers.
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