Title |
The Gut Microbiome as Therapeutic Target in Central Nervous System Diseases: Implications for Stroke
|
---|---|
Published in |
Neurotherapeutics, October 2016
|
DOI | 10.1007/s13311-016-0475-x |
Pubmed ID | |
Authors |
Katarzyna Winek, Ulrich Dirnagl, Andreas Meisel |
Abstract |
Research on commensal microbiota and its contribution to health and disease is a new and very dynamically developing field of biology and medicine. Recent experimental and clinical investigations underscore the importance of gut microbiota in the pathogenesis and course of stroke. Importantly, microbiota may influence the outcome of cerebral ischemia by modulating central nervous system antigen-specific immune responses. In this review we summarize studies linking gut microbiota with physiological function and disorders of the central nervous system. Based on these insights we speculate about targeting the gut microbiome in order to treat stroke. |
X Demographics
The data shown below were collected from the profiles of 9 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
Country | Count | As % |
---|---|---|
Venezuela, Bolivarian Republic of | 1 | 11% |
United States | 1 | 11% |
Unknown | 7 | 78% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 8 | 89% |
Scientists | 1 | 11% |
Mendeley readers
The data shown below were compiled from readership statistics for 275 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
Country | Count | As % |
---|---|---|
South Africa | 1 | <1% |
Brazil | 1 | <1% |
Unknown | 273 | 99% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 45 | 16% |
Student > Ph. D. Student | 33 | 12% |
Student > Bachelor | 31 | 11% |
Student > Master | 26 | 9% |
Student > Postgraduate | 17 | 6% |
Other | 67 | 24% |
Unknown | 56 | 20% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 49 | 18% |
Agricultural and Biological Sciences | 42 | 15% |
Biochemistry, Genetics and Molecular Biology | 25 | 9% |
Neuroscience | 25 | 9% |
Immunology and Microbiology | 16 | 6% |
Other | 42 | 15% |
Unknown | 76 | 28% |
Attention Score in Context
This research output has an Altmetric Attention Score of 16. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 30 January 2024.
All research outputs
#2,236,279
of 25,373,627 outputs
Outputs from Neurotherapeutics
#196
of 1,308 outputs
Outputs of similar age
#37,976
of 327,136 outputs
Outputs of similar age from Neurotherapeutics
#4
of 15 outputs
Altmetric has tracked 25,373,627 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 91st percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,308 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 18.2. This one has done well, scoring higher than 84% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 327,136 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 88% of its contemporaries.
We're also able to compare this research output to 15 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 73% of its contemporaries.