Title |
Metagenomic identification of viral pathogens
|
---|---|
Published in |
Trends in Biotechnology, February 2013
|
DOI | 10.1016/j.tibtech.2013.01.016 |
Pubmed ID | |
Authors |
Kyle Bibby |
Abstract |
The target-independent identification of viral pathogens using 'shotgun' metagenomic sequencing is an emerging approach with potentially wide applications in clinical diagnostics, public health monitoring, and viral discovery. In this approach, all viral nucleic acids present in a sample are sequenced in a random, shotgun manner. Pathogens are then identified without the prerequisite of searching for a specific viral pathogen. In this opinion article, I discuss the current state and future research directions for this emerging and disruptive technology. With further technical developments, viral metagenomics has the potential to be deployed as a powerful and widely adopted tool, transforming the way that viral disease is researched, monitored, and treated. |
X Demographics
Geographical breakdown
Country | Count | As % |
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United States | 4 | 57% |
Unknown | 3 | 43% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 3 | 43% |
Science communicators (journalists, bloggers, editors) | 2 | 29% |
Scientists | 2 | 29% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 6 | 2% |
Brazil | 5 | 2% |
United Kingdom | 3 | 1% |
South Africa | 2 | <1% |
Sweden | 2 | <1% |
Portugal | 1 | <1% |
Israel | 1 | <1% |
Australia | 1 | <1% |
Switzerland | 1 | <1% |
Other | 7 | 3% |
Unknown | 248 | 90% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 59 | 21% |
Researcher | 52 | 19% |
Student > Master | 38 | 14% |
Student > Bachelor | 36 | 13% |
Professor > Associate Professor | 15 | 5% |
Other | 45 | 16% |
Unknown | 32 | 12% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 120 | 43% |
Biochemistry, Genetics and Molecular Biology | 37 | 13% |
Immunology and Microbiology | 18 | 6% |
Medicine and Dentistry | 15 | 5% |
Environmental Science | 11 | 4% |
Other | 32 | 12% |
Unknown | 44 | 16% |