Title |
Surface-enhanced Raman scattering in cancer detection and imaging
|
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Published in |
Trends in Biotechnology, February 2013
|
DOI | 10.1016/j.tibtech.2013.01.013 |
Pubmed ID | |
Authors |
Marc Vendrell, Kaustabh Kumar Maiti, Kevin Dhaliwal, Young-Tae Chang |
Abstract |
Technologies that use surface-enhanced Raman scattering (SERS) have experienced significant growth in biomedical research during the past 4 years. In this review we summarize the progress in SERS for cancer diagnostics, including multiplexed detection and identification of new biomarkers, single-nucleotide polymorphisms, and circulating tumor cells. SERS is also used as a non-invasive tool for cancer imaging with immunoSERS microscopy, histological analysis of biopsies, and in vivo detection of tumors. We discuss the future of SERS probes compatible with multiple imaging modalities and their potential for clinical translation (e.g., endoscope-based and intraoperative imaging as tools for surgical guidance). Moreover, we highlight the potential of SERS agents for targeted drug delivery and photothermal therapy. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 2 | 50% |
Japan | 1 | 25% |
United Kingdom | 1 | 25% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Scientists | 2 | 50% |
Science communicators (journalists, bloggers, editors) | 1 | 25% |
Members of the public | 1 | 25% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
France | 2 | <1% |
Malaysia | 1 | <1% |
India | 1 | <1% |
United Kingdom | 1 | <1% |
Mexico | 1 | <1% |
China | 1 | <1% |
United States | 1 | <1% |
Unknown | 329 | 98% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 101 | 30% |
Researcher | 50 | 15% |
Student > Bachelor | 41 | 12% |
Student > Master | 31 | 9% |
Student > Doctoral Student | 21 | 6% |
Other | 54 | 16% |
Unknown | 39 | 12% |
Readers by discipline | Count | As % |
---|---|---|
Chemistry | 85 | 25% |
Engineering | 39 | 12% |
Physics and Astronomy | 36 | 11% |
Agricultural and Biological Sciences | 34 | 10% |
Materials Science | 28 | 8% |
Other | 59 | 18% |
Unknown | 56 | 17% |