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Fundamentals of aerosol therapy in critical care

Overview of attention for article published in Critical Care, October 2016
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (89th percentile)
  • Good Attention Score compared to outputs of the same age and source (66th percentile)

Mentioned by

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28 X users
facebook
6 Facebook pages

Citations

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81 Dimensions

Readers on

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263 Mendeley
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Title
Fundamentals of aerosol therapy in critical care
Published in
Critical Care, October 2016
DOI 10.1186/s13054-016-1448-5
Pubmed ID
Authors

Jayesh Dhanani, John F. Fraser, Hak-Kim Chan, Jordi Rello, Jeremy Cohen, Jason A. Roberts

Abstract

Drug dosing in critically ill patients is challenging due to the altered drug pharmacokinetics-pharmacodynamics associated with systemic therapies. For many drug therapies, there is potential to use the respiratory system as an alternative route for drug delivery. Aerosol drug delivery can provide many advantages over conventional therapy. Given that respiratory diseases are the commonest causes of critical illness, use of aerosol therapy to provide high local drug concentrations with minimal systemic side effects makes this route an attractive option. To date, limited evidence has restricted its wider application. The efficacy of aerosol drug therapy depends on drug-related factors (particle size, molecular weight), device factors, patient-related factors (airway anatomy, inhalation patterns) and mechanical ventilation-related factors (humidification, airway). This review identifies the relevant factors which require attention for optimization of aerosol drug delivery that can achieve better drug concentrations at the target sites and potentially improve clinical outcomes.

X Demographics

X Demographics

The data shown below were collected from the profiles of 28 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 263 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Chile 1 <1%
Italy 1 <1%
South Africa 1 <1%
Czechia 1 <1%
Mexico 1 <1%
Unknown 258 98%

Demographic breakdown

Readers by professional status Count As %
Other 38 14%
Researcher 32 12%
Student > Master 28 11%
Student > Ph. D. Student 26 10%
Student > Bachelor 21 8%
Other 58 22%
Unknown 60 23%
Readers by discipline Count As %
Medicine and Dentistry 106 40%
Nursing and Health Professions 23 9%
Pharmacology, Toxicology and Pharmaceutical Science 17 6%
Biochemistry, Genetics and Molecular Biology 10 4%
Agricultural and Biological Sciences 8 3%
Other 29 11%
Unknown 70 27%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 18. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 17 February 2024.
All research outputs
#2,032,628
of 25,374,917 outputs
Outputs from Critical Care
#1,820
of 6,554 outputs
Outputs of similar age
#34,972
of 327,752 outputs
Outputs of similar age from Critical Care
#36
of 109 outputs
Altmetric has tracked 25,374,917 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 91st percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 6,554 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 20.8. This one has gotten more attention than average, scoring higher than 72% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 327,752 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 89% of its contemporaries.
We're also able to compare this research output to 109 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 66% of its contemporaries.