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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Variation in Antiviral Protection Mediated by Different Wolbachia Strains in Drosophila simulans
|
|---|---|
| Published in |
PLoS Pathogens, November 2009
|
| DOI | 10.1371/journal.ppat.1000656 |
| Pubmed ID | |
| Authors |
Sheree E. Osborne, Yi San Leong, Scott L. O'Neill, Karyn N. Johnson |
| Abstract |
Drosophila C virus (DCV) is a natural pathogen of Drosophila and a useful model for studying antiviral defences. The Drosophila host is also commonly infected with the widespread endosymbiotic bacteria Wolbachia pipientis. When DCV coinfects Wolbachia-infected D. melanogaster, virus particles accumulate more slowly and virus induced mortality is substantially delayed. Considering that Wolbachia is estimated to infect up to two-thirds of all insect species, the observed protective effects of Wolbachia may extend to a range of both beneficial and pest insects, including insects that vector important viral diseases of humans, animals and plants. Currently, Wolbachia-mediated antiviral protection has only been described from a limited number of very closely related strains that infect D. melanogaster. We used D. simulans and its naturally occurring Wolbachia infections to test the generality of the Wolbachia-mediated antiviral protection. We generated paired D. simulans lines either uninfected or infected with five different Wolbachia strains. Each paired fly line was challenged with DCV and Flock House virus. Significant antiviral protection was seen for some but not all of the Wolbachia strain-fly line combinations tested. In some cases, protection from virus-induced mortality was associated with a delay in virus accumulation, but some Wolbachia-infected flies were tolerant to high titres of DCV. The Wolbachia strains that did protect occurred at comparatively high density within the flies and were most closely related to the D. melanogaster Wolbachia strain wMel. These results indicate that Wolbachia-mediated antiviral protection is not ubiquitous, a finding that is important for understanding the distribution of Wolbachia and virus in natural insect populations. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Scientists | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 306 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 5 | 2% |
| United Kingdom | 4 | 1% |
| Portugal | 2 | <1% |
| France | 2 | <1% |
| Japan | 2 | <1% |
| Ghana | 1 | <1% |
| Brazil | 1 | <1% |
| Czechia | 1 | <1% |
| Germany | 1 | <1% |
| Other | 2 | <1% |
| Unknown | 285 | 93% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 70 | 23% |
| Researcher | 61 | 20% |
| Student > Master | 44 | 14% |
| Student > Bachelor | 34 | 11% |
| Student > Doctoral Student | 12 | 4% |
| Other | 42 | 14% |
| Unknown | 43 | 14% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 182 | 59% |
| Biochemistry, Genetics and Molecular Biology | 45 | 15% |
| Environmental Science | 8 | 3% |
| Immunology and Microbiology | 7 | 2% |
| Medicine and Dentistry | 5 | 2% |
| Other | 12 | 4% |
| Unknown | 47 | 15% |
Attention Score in Context
This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 28 February 2013.
All research outputs
#7,960,693
of 25,374,917 outputs
Outputs from PLoS Pathogens
#5,855
of 9,468 outputs
Outputs of similar age
#35,711
of 106,461 outputs
Outputs of similar age from PLoS Pathogens
#32
of 80 outputs
Altmetric has tracked 25,374,917 research outputs across all sources so far. This one has received more attention than most of these and is in the 67th percentile.
So far Altmetric has tracked 9,468 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 20.4. This one is in the 36th percentile – i.e., 36% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 106,461 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 65% of its contemporaries.
We're also able to compare this research output to 80 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 58% of its contemporaries.