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Causes of variation in the neutrophillymphocyte and plateletlymphocyte ratios: a twin-family study

Overview of attention for article published in Biomarkers in Medicine, October 2016
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Title
Causes of variation in the neutrophillymphocyte and plateletlymphocyte ratios: a twin-family study
Published in
Biomarkers in Medicine, October 2016
DOI 10.2217/bmm-2016-0147
Pubmed ID
Authors

Bochao D Lin, Jouke-Jan Hottenga, Abdel Abdellaoui, Conor V Dolan, Eco J C de Geus, Cornelis Kluft, Dorret I Boomsma, Gonneke Willemsen

Abstract

Neutrophil-lymphocyte ratio (NLR) and platelet-lymphocyte ratio (PLR) are biomarkers for disease development, for whom little is known about causes of variation in the general population. We estimated the heritability of PLR and NLR and examined their association with gender, demographic, lifestyle and environmental factors in a Dutch nonpatient twin family population (n = 8108). Heritability was estimated at 64% for PLR and 36% for NLR. Men had on average higher NLR, but lower PLR levels than women. PLR and NLR increased significantly with age, decreased in colder months and showed small but significant sex- and age-specific associations with body composition and smoking. NLR and PLR levels are heritable and influenced by age, sex and environmental factors, such as seasonal conditions and lifestyle.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 70 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 70 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 13 19%
Student > Ph. D. Student 7 10%
Student > Master 5 7%
Researcher 5 7%
Other 5 7%
Other 8 11%
Unknown 27 39%
Readers by discipline Count As %
Medicine and Dentistry 22 31%
Nursing and Health Professions 5 7%
Biochemistry, Genetics and Molecular Biology 4 6%
Pharmacology, Toxicology and Pharmaceutical Science 2 3%
Psychology 2 3%
Other 4 6%
Unknown 31 44%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 14 October 2016.
All research outputs
#20,655,488
of 25,371,288 outputs
Outputs from Biomarkers in Medicine
#499
of 735 outputs
Outputs of similar age
#254,424
of 329,203 outputs
Outputs of similar age from Biomarkers in Medicine
#18
of 20 outputs
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So far Altmetric has tracked 735 research outputs from this source. They receive a mean Attention Score of 4.7. This one is in the 15th percentile – i.e., 15% of its peers scored the same or lower than it.
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We're also able to compare this research output to 20 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.