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Recent progress in adjuvant discovery for peptide-based subunit vaccines

Overview of attention for article published in Human vaccines immunotherapeutics, December 2013
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (95th percentile)
  • High Attention Score compared to outputs of the same age and source (92nd percentile)

Mentioned by

news
2 news outlets
twitter
10 X users
patent
3 patents
wikipedia
2 Wikipedia pages

Citations

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195 Dimensions

Readers on

mendeley
212 Mendeley
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Title
Recent progress in adjuvant discovery for peptide-based subunit vaccines
Published in
Human vaccines immunotherapeutics, December 2013
DOI 10.4161/hv.27332
Pubmed ID
Authors

Fazren Azmi, Abdullah Al Hadi Ahmad Fuaad, Mariusz Skwarczynski, Istvan Toth

Abstract

Peptide-based subunit vaccines are of great interest in modern immunotherapy as they are safe, easy to produce and well defined. However, peptide antigens produce a relatively weak immune response, and thus require the use of immunostimulants (adjuvants) for optimal efficacy. Developing a safe and effective adjuvant remains a challenge for peptide-based vaccine design. Recent advances in immunology have allowed researchers to have a better understanding of the immunological implication of related diseases, which facilitates more rational design of adjuvant systems. Understanding the molecular structure of the adjuvants allows the establishment of their structure-activity relationships which is useful for the development of next-generation adjuvants. This review summarizes the current state of adjuvants development in the field of synthetic peptide-based vaccines. The structural, chemical and biological properties of adjuvants associated with their immunomodulatory effects are discussed.

X Demographics

X Demographics

The data shown below were collected from the profiles of 10 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 212 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 <1%
United States 1 <1%
Germany 1 <1%
South Africa 1 <1%
Unknown 208 98%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 37 17%
Student > Master 25 12%
Researcher 22 10%
Student > Bachelor 22 10%
Student > Doctoral Student 11 5%
Other 34 16%
Unknown 61 29%
Readers by discipline Count As %
Agricultural and Biological Sciences 30 14%
Biochemistry, Genetics and Molecular Biology 29 14%
Immunology and Microbiology 20 9%
Chemistry 17 8%
Pharmacology, Toxicology and Pharmaceutical Science 13 6%
Other 30 14%
Unknown 73 34%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 30. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 20 February 2024.
All research outputs
#1,304,584
of 25,374,917 outputs
Outputs from Human vaccines immunotherapeutics
#285
of 3,845 outputs
Outputs of similar age
#13,998
of 320,279 outputs
Outputs of similar age from Human vaccines immunotherapeutics
#5
of 64 outputs
Altmetric has tracked 25,374,917 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 94th percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 3,845 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 14.3. This one has done particularly well, scoring higher than 92% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 320,279 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 95% of its contemporaries.
We're also able to compare this research output to 64 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 92% of its contemporaries.