| Title |
Biogenesis of extracellular vesicles (EV): exosomes, microvesicles, retrovirus-like vesicles, and apoptotic bodies
|
|---|---|
| Published in |
Journal of Neuro-Oncology, March 2013
|
| DOI | 10.1007/s11060-013-1084-8 |
| Pubmed ID | |
| Authors |
Johnny C. Akers, David Gonda, Ryan Kim, Bob S. Carter, Clark C. Chen |
| Abstract |
Recent studies suggest both normal and cancerous cells secrete vesicles into the extracellular space. These extracellular vesicles (EVs) contain materials that mirror the genetic and proteomic content of the secreting cell. The identification of cancer-specific material in EVs isolated from the biofluids (e.g., serum, cerebrospinal fluid, urine) of cancer patients suggests EVs as an attractive platform for biomarker development. It is important to recognize that the EVs derived from clinical samples are likely highly heterogeneous in make-up and arose from diverse sets of biologic processes. This article aims to review the biologic processes that give rise to various types of EVs, including exosomes, microvesicles, retrovirus like particles, and apoptotic bodies. Clinical pertinence of these EVs to neuro-oncology will also be discussed. |
X Demographics
The data shown below were collected from the profiles of 4 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Netherlands | 1 | 25% |
| United States | 1 | 25% |
| Unknown | 2 | 50% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 4 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 1,164 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 4 | <1% |
| Denmark | 3 | <1% |
| United Kingdom | 3 | <1% |
| Poland | 2 | <1% |
| Brazil | 2 | <1% |
| Netherlands | 1 | <1% |
| Switzerland | 1 | <1% |
| Canada | 1 | <1% |
| France | 1 | <1% |
| Other | 4 | <1% |
| Unknown | 1142 | 98% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 202 | 17% |
| Student > Master | 166 | 14% |
| Student > Bachelor | 161 | 14% |
| Researcher | 119 | 10% |
| Student > Doctoral Student | 75 | 6% |
| Other | 102 | 9% |
| Unknown | 339 | 29% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 285 | 24% |
| Agricultural and Biological Sciences | 198 | 17% |
| Medicine and Dentistry | 109 | 9% |
| Pharmacology, Toxicology and Pharmaceutical Science | 46 | 4% |
| Immunology and Microbiology | 41 | 4% |
| Other | 125 | 11% |
| Unknown | 360 | 31% |
Attention Score in Context
This research output has an Altmetric Attention Score of 14. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 08 August 2023.
All research outputs
#2,597,358
of 25,837,817 outputs
Outputs from Journal of Neuro-Oncology
#148
of 3,302 outputs
Outputs of similar age
#20,689
of 209,573 outputs
Outputs of similar age from Journal of Neuro-Oncology
#2
of 32 outputs
Altmetric has tracked 25,837,817 research outputs across all sources so far. Compared to these this one has done well and is in the 89th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 3,302 research outputs from this source. They receive a mean Attention Score of 4.5. This one has done particularly well, scoring higher than 95% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 209,573 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 89% of its contemporaries.
We're also able to compare this research output to 32 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 93% of its contemporaries.