Title |
Marine actinomycetes as a source of novel secondary metabolites
|
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Published in |
Antonie van Leeuwenhoek, January 2005
|
DOI | 10.1007/s10482-004-6538-8 |
Pubmed ID | |
Authors |
Hans-Peter Fiedler, Christina Bruntner, Alan T. Bull, Alan C. Ward, Michael Goodfellow, Olivier Potterat, Carsten Puder, Gerhard Mihm |
Abstract |
A set of 600 actinomycetes strains which were isolated from marine sediments from various sites in the Pacific and Atlantic Oceans were screened for the production of bioactive secondary metabolites. Marine streptomycete strains were found to be producers of well known chemically diverse antibiotics isolated from terrestrial streptomycetes, as in the case of marine Micromonospora strains. New marine members of the rare genus Verrucosispora seem to be a promising source for novel bioactive secondary metabolites as shown in the case of the abyssomicin producing strain AB-18-032. |
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Geographical breakdown
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Brazil | 4 | 2% |
India | 3 | 1% |
Saudi Arabia | 2 | <1% |
United States | 2 | <1% |
Spain | 2 | <1% |
Malaysia | 1 | <1% |
South Africa | 1 | <1% |
France | 1 | <1% |
Indonesia | 1 | <1% |
Other | 4 | 2% |
Unknown | 240 | 92% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 54 | 21% |
Researcher | 42 | 16% |
Student > Master | 41 | 16% |
Student > Bachelor | 29 | 11% |
Student > Postgraduate | 15 | 6% |
Other | 40 | 15% |
Unknown | 40 | 15% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 106 | 41% |
Biochemistry, Genetics and Molecular Biology | 44 | 17% |
Chemistry | 32 | 12% |
Immunology and Microbiology | 11 | 4% |
Environmental Science | 8 | 3% |
Other | 15 | 6% |
Unknown | 45 | 17% |