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X Demographics
Mendeley readers
Attention Score in Context
| Title |
A variant in FTO shows association with melanoma risk not due to BMI
|
|---|---|
| Published in |
Nature Genetics, March 2013
|
| DOI | 10.1038/ng.2571 |
| Pubmed ID | |
| Abstract |
We report the results of an association study of melanoma that is based on the genome-wide imputation of the genotypes of 1,353 cases and 3,566 controls of European origin conducted by the GenoMEL consortium. This revealed an association between several SNPs in intron 8 of the FTO gene, including rs16953002, which replicated using 12,313 cases and 55,667 controls of European ancestry from Europe, the USA and Australia (combined P = 3.6 × 10(-12), per-allele odds ratio for allele A = 1.16). In addition to identifying a new melanoma-susceptibility locus, this is to our knowledge the first study to identify and replicate an association with SNPs in FTO not related to body mass index (BMI). These SNPs are not in intron 1 (the BMI-related region) and exhibit no association with BMI. This suggests FTO's function may be broader than the existing paradigm that FTO variants influence multiple traits only through their associations with BMI and obesity. |
X Demographics
The data shown below were collected from the profiles of 10 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 2 | 20% |
| Australia | 2 | 20% |
| Germany | 1 | 10% |
| Unknown | 5 | 50% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 4 | 40% |
| Practitioners (doctors, other healthcare professionals) | 3 | 30% |
| Scientists | 3 | 30% |
Mendeley readers
The data shown below were compiled from readership statistics for 128 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 5 | 4% |
| Australia | 1 | <1% |
| Italy | 1 | <1% |
| Mexico | 1 | <1% |
| Egypt | 1 | <1% |
| Unknown | 119 | 93% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 35 | 27% |
| Student > Ph. D. Student | 23 | 18% |
| Professor | 11 | 9% |
| Professor > Associate Professor | 9 | 7% |
| Student > Bachelor | 9 | 7% |
| Other | 27 | 21% |
| Unknown | 14 | 11% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 38 | 30% |
| Biochemistry, Genetics and Molecular Biology | 31 | 24% |
| Medicine and Dentistry | 30 | 23% |
| Pharmacology, Toxicology and Pharmaceutical Science | 2 | 2% |
| Nursing and Health Professions | 2 | 2% |
| Other | 8 | 6% |
| Unknown | 17 | 13% |
Attention Score in Context
This research output has an Altmetric Attention Score of 72. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 19 January 2021.
All research outputs
#516,135
of 23,299,593 outputs
Outputs from Nature Genetics
#1,081
of 7,250 outputs
Outputs of similar age
#3,555
of 195,958 outputs
Outputs of similar age from Nature Genetics
#19
of 80 outputs
Altmetric has tracked 23,299,593 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 97th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 7,250 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 41.5. This one has done well, scoring higher than 85% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 195,958 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 98% of its contemporaries.
We're also able to compare this research output to 80 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 77% of its contemporaries.