Title |
Post-weaning selenium and folate supplementation affects gene and protein expression and global DNA methylation in mice fed high-fat diets
|
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Published in |
BMC Medical Genomics, March 2013
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DOI | 10.1186/1755-8794-6-7 |
Pubmed ID | |
Authors |
Emma N Bermingham, Shalome A Bassett, Wayne Young, Nicole C Roy, Warren C McNabb, Janine M Cooney, Di T Brewster, William A Laing, Matthew PG Barnett |
Abstract |
Consumption of high-fat diets has negative impacts on health and well-being, some of which may be epigenetically regulated. Selenium and folate are two compounds which influence epigenetic mechanisms. We investigated the hypothesis that post-weaning supplementation with adequate levels of selenium and folate in offspring of female mice fed a high-fat, low selenium and folate diet during gestation and lactation will lead to epigenetic changes of potential importance for long-term health. |
Mendeley readers
The data shown below were compiled from readership statistics for 57 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
Country | Count | As % |
---|---|---|
Poland | 2 | 4% |
United Kingdom | 1 | 2% |
Portugal | 1 | 2% |
Canada | 1 | 2% |
Unknown | 52 | 91% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Master | 10 | 18% |
Student > Ph. D. Student | 9 | 16% |
Researcher | 8 | 14% |
Student > Bachelor | 4 | 7% |
Lecturer | 4 | 7% |
Other | 8 | 14% |
Unknown | 14 | 25% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 16 | 28% |
Biochemistry, Genetics and Molecular Biology | 9 | 16% |
Medicine and Dentistry | 8 | 14% |
Nursing and Health Professions | 3 | 5% |
Unspecified | 1 | 2% |
Other | 6 | 11% |
Unknown | 14 | 25% |