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Post-weaning selenium and folate supplementation affects gene and protein expression and global DNA methylation in mice fed high-fat diets

Overview of attention for article published in BMC Medical Genomics, March 2013
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Title
Post-weaning selenium and folate supplementation affects gene and protein expression and global DNA methylation in mice fed high-fat diets
Published in
BMC Medical Genomics, March 2013
DOI 10.1186/1755-8794-6-7
Pubmed ID
Authors

Emma N Bermingham, Shalome A Bassett, Wayne Young, Nicole C Roy, Warren C McNabb, Janine M Cooney, Di T Brewster, William A Laing, Matthew PG Barnett

Abstract

Consumption of high-fat diets has negative impacts on health and well-being, some of which may be epigenetically regulated. Selenium and folate are two compounds which influence epigenetic mechanisms. We investigated the hypothesis that post-weaning supplementation with adequate levels of selenium and folate in offspring of female mice fed a high-fat, low selenium and folate diet during gestation and lactation will lead to epigenetic changes of potential importance for long-term health.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 57 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Poland 2 4%
United Kingdom 1 2%
Portugal 1 2%
Canada 1 2%
Unknown 52 91%

Demographic breakdown

Readers by professional status Count As %
Student > Master 10 18%
Student > Ph. D. Student 9 16%
Researcher 8 14%
Student > Bachelor 4 7%
Lecturer 4 7%
Other 8 14%
Unknown 14 25%
Readers by discipline Count As %
Agricultural and Biological Sciences 16 28%
Biochemistry, Genetics and Molecular Biology 9 16%
Medicine and Dentistry 8 14%
Nursing and Health Professions 3 5%
Unspecified 1 2%
Other 6 11%
Unknown 14 25%