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Vancomycin minimum inhibitory concentration, host comorbidities and mortality in Staphylococcus aureus bacteraemia

Overview of attention for article published in Clinical Microbiology and Infection, February 2013
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Citations

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22 Dimensions

Readers on

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32 Mendeley
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Title
Vancomycin minimum inhibitory concentration, host comorbidities and mortality in Staphylococcus aureus bacteraemia
Published in
Clinical Microbiology and Infection, February 2013
DOI 10.1111/1469-0691.12168
Pubmed ID
Authors

N. E. Holmes, J. D. Turnidge, W. J. Munckhof, J. O. Robinson, T. M. Korman, M. V. N. O'Sullivan, T. L. Anderson, S. A. Roberts, S. J. C. Warren, W. Gao, P. D. R. Johnson, B. P. Howden

Abstract

We reported an association between elevated vancomycin MIC and 30-day mortality in patients with Staphylococcus aureus bacteraemia (SAB), including patients with methicillin-susceptible S. aureus (MSSA) treated with flucloxacillin. A detailed analysis of comorbidities and disease severity scores in the same cohort of patients was performed to ascertain if unknown clinical parameters may have influenced these results. The association between elevated vancomycin MIC and 30-day mortality in SAB remained significant (p 0.001) on multivariable logistic regression analysis even when accounting for clinical factors. In addition, the association persisted when restricting analysis to patients with MSSA bacteraemia treated with flucloxacillin. This suggests that elevated vancomycin MIC is associated with but not causally linked to an organism factor that is responsible for increased mortality.

X Demographics

X Demographics

The data shown below were collected from the profiles of 5 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 32 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Spain 1 3%
Unknown 31 97%

Demographic breakdown

Readers by professional status Count As %
Researcher 11 34%
Student > Bachelor 4 13%
Other 4 13%
Student > Master 2 6%
Student > Ph. D. Student 2 6%
Other 3 9%
Unknown 6 19%
Readers by discipline Count As %
Medicine and Dentistry 15 47%
Biochemistry, Genetics and Molecular Biology 4 13%
Immunology and Microbiology 2 6%
Agricultural and Biological Sciences 2 6%
Pharmacology, Toxicology and Pharmaceutical Science 1 3%
Other 2 6%
Unknown 6 19%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 03 December 2013.
All research outputs
#14,277,392
of 25,373,627 outputs
Outputs from Clinical Microbiology and Infection
#2,955
of 4,641 outputs
Outputs of similar age
#107,878
of 205,032 outputs
Outputs of similar age from Clinical Microbiology and Infection
#39
of 68 outputs
Altmetric has tracked 25,373,627 research outputs across all sources so far. This one is in the 43rd percentile – i.e., 43% of other outputs scored the same or lower than it.
So far Altmetric has tracked 4,641 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 17.7. This one is in the 35th percentile – i.e., 35% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 205,032 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 47th percentile – i.e., 47% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 68 others from the same source and published within six weeks on either side of this one. This one is in the 41st percentile – i.e., 41% of its contemporaries scored the same or lower than it.