| Title |
MicroRNA—implications for cancer
|
|---|---|
| Published in |
Virchows Archiv, November 2007
|
| DOI | 10.1007/s00428-007-0532-2 |
| Pubmed ID | |
| Authors |
Stefanie Sassen, Eric A. Miska, Carlos Caldas |
| Abstract |
MicroRNAs (miRNAs) are small RNA molecules that regulate gene expression post-transcriptionally. After the discovery of the first miRNA in the roundworm Caenorhabditis elegans, these short regulatory RNAs have been found to be an abundant class of RNAs in plants, animals, and DNA viruses. About 3% of human genes encode for miRNAs, and up to 30% of human protein coding genes may be regulated by miRNAs. MicroRNAs play a key role in diverse biological processes, including development, cell proliferation, differentiation, and apoptosis. Accordingly, altered miRNA expression is likely to contribute to human disease, including cancer. This review will summarize the emerging knowledge of the connections between human miRNA biology and different aspects of carcinogenesis. Various techniques available to investigate miRNAs will also be discussed. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 408 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 6 | 1% |
| India | 5 | 1% |
| Brazil | 4 | <1% |
| United Kingdom | 3 | <1% |
| Norway | 2 | <1% |
| Mexico | 2 | <1% |
| Korea, Republic of | 1 | <1% |
| Germany | 1 | <1% |
| Malaysia | 1 | <1% |
| Other | 5 | 1% |
| Unknown | 378 | 93% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 106 | 26% |
| Student > Master | 71 | 17% |
| Researcher | 60 | 15% |
| Student > Bachelor | 50 | 12% |
| Professor > Associate Professor | 21 | 5% |
| Other | 65 | 16% |
| Unknown | 35 | 9% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 193 | 47% |
| Biochemistry, Genetics and Molecular Biology | 68 | 17% |
| Medicine and Dentistry | 52 | 13% |
| Chemistry | 16 | 4% |
| Engineering | 11 | 3% |
| Other | 25 | 6% |
| Unknown | 43 | 11% |
Attention Score in Context
This research output has an Altmetric Attention Score of 18. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 22 July 2020.
All research outputs
#1,767,607
of 22,699,621 outputs
Outputs from Virchows Archiv
#41
of 1,934 outputs
Outputs of similar age
#6,309
of 155,922 outputs
Outputs of similar age from Virchows Archiv
#1
of 6 outputs
Altmetric has tracked 22,699,621 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 92nd percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,934 research outputs from this source. They receive a mean Attention Score of 4.0. This one has done particularly well, scoring higher than 97% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 155,922 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 95% of its contemporaries.
We're also able to compare this research output to 6 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them