Title |
Altered glucose profiles and risk for hypoglycaemia during oral glucose tolerance testing in pregnancies after gastric bypass surgery
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Published in |
Diabetologia, October 2016
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DOI | 10.1007/s00125-016-4128-8 |
Pubmed ID | |
Authors |
Michael Feichtinger, Tina Stopp, Sandra Hofmann, Stephanie Springer, Sophie Pils, Alexandra Kautzky-Willer, Herbert Kiss, Wolfgang Eppel, Andrea Tura, Latife Bozkurt, Christian S. Göbl |
Abstract |
A history of gastric bypass surgery can influence the results of the OGTT recommended during pregnancy. Therefore, we compared OGTT glucose kinetics and pregnancy outcome between pregnant gastric bypass patients and BMI-matched, lean and obese controls. Medical records were used to collect data on glucose measurements during the 2 h 75 g OGTT as well as on pregnancy and fetal outcome for 304 women (n = 76 per group, matched for age and date of delivery). Women after bariatric surgery had lower fasting glucose levels compared with lean, obese and BMI-matched controls, and showed altered postprandial glucose kinetics, including a rise at 60 min followed by hypoglycaemia with serum glucose of <3.34 mmol/l (which occurred in 54.8%). Moreover, their risk of pre-eclampsia or gestational hypertension was reduced, with an increased risk of delivering small for gestational age infants. Alternative strategies to accurately define impaired glucose metabolism in pregnancies after bariatric surgery should be explored. |
X Demographics
Geographical breakdown
Country | Count | As % |
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United Kingdom | 4 | 29% |
Greece | 1 | 7% |
Egypt | 1 | 7% |
India | 1 | 7% |
United States | 1 | 7% |
France | 1 | 7% |
Brazil | 1 | 7% |
Austria | 1 | 7% |
Unknown | 3 | 21% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 8 | 57% |
Scientists | 5 | 36% |
Practitioners (doctors, other healthcare professionals) | 1 | 7% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 72 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Master | 10 | 14% |
Student > Bachelor | 10 | 14% |
Researcher | 10 | 14% |
Student > Ph. D. Student | 6 | 8% |
Other | 5 | 7% |
Other | 8 | 11% |
Unknown | 23 | 32% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 28 | 39% |
Nursing and Health Professions | 4 | 6% |
Biochemistry, Genetics and Molecular Biology | 2 | 3% |
Engineering | 2 | 3% |
Agricultural and Biological Sciences | 2 | 3% |
Other | 8 | 11% |
Unknown | 26 | 36% |