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Sperm DNA fragmentation in men with malignancy

Overview of attention for article published in Fertility & Sterility, March 2013
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1 X user
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1 research highlight platform

Citations

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15 Dimensions

Readers on

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29 Mendeley
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Title
Sperm DNA fragmentation in men with malignancy
Published in
Fertility & Sterility, March 2013
DOI 10.1016/j.fertnstert.2013.02.015
Pubmed ID
Authors

Simon McDowell, Keith Harrison, Ben Kroon, Emily Ford, Anusch Yazdani

Abstract

To determine if men with malignancy have increased sperm DNA fragmentation compared with men presenting for sperm donation. Retrospective observational study. Tertiary-level fertility center. Eighty-nine men with cancer presenting for prophylactic semen cryopreservation and 35 men presenting for sperm donation. None. Sperm DNA fragmentation index (DFI) measured by sperm chromatin assay. The mean sperm DFI in men with a diagnosis of cancer, 9.88% (95% confidence interval [CI] 7.84%-12.44%), did not differ from that found in men presenting for sperm donation 10.46% (95% CI 8.68%-11.80%). There were no significant differences in mean sperm DFI within cancer subgroups or when comparing testicular and nontesticular cancers. Subgroup analysis lacked statistical power. Men with testicular cancer have significantly reduced sperm concentration compared with both control subjects and men with nontesticular cancer. In our study population there was no difference in sperm DFI between men undergoing prophylactic semen cryopreservation and men presenting for sperm donation. Sperm DFI assessment has limited utility in the routine evaluation of men presenting for semen cryopreservation.

X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 29 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Canada 1 3%
Unknown 28 97%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 4 14%
Researcher 4 14%
Other 3 10%
Unspecified 3 10%
Student > Master 3 10%
Other 6 21%
Unknown 6 21%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 8 28%
Medicine and Dentistry 7 24%
Unspecified 3 10%
Agricultural and Biological Sciences 2 7%
Psychology 1 3%
Other 1 3%
Unknown 7 24%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 16 July 2013.
All research outputs
#16,063,069
of 25,394,764 outputs
Outputs from Fertility & Sterility
#6,887
of 9,378 outputs
Outputs of similar age
#123,187
of 207,818 outputs
Outputs of similar age from Fertility & Sterility
#67
of 111 outputs
Altmetric has tracked 25,394,764 research outputs across all sources so far. This one is in the 34th percentile – i.e., 34% of other outputs scored the same or lower than it.
So far Altmetric has tracked 9,378 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 11.1. This one is in the 24th percentile – i.e., 24% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 207,818 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 38th percentile – i.e., 38% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 111 others from the same source and published within six weeks on either side of this one. This one is in the 31st percentile – i.e., 31% of its contemporaries scored the same or lower than it.