Title |
Characteristics of Autism Spectrum Disorder in Sotos Syndrome
|
---|---|
Published in |
Journal of Autism and Developmental Disorders, October 2016
|
DOI | 10.1007/s10803-016-2941-z |
Pubmed ID | |
Authors |
Chloe Lane, Elizabeth Milne, Megan Freeth |
Abstract |
Sotos syndrome is a congenital overgrowth disorder with an incidence of approximately 1 in 14,000. This study investigated behavioural characteristics of ASD within a large cohort of individuals with Sotos syndrome (n = 78). As measured by the Social Responsiveness Scale, second edition (SRS-2), 65 participants (83.33 %) met clinical cut-off (T-score ≥60). There was no significant gender difference in symptom severity. There was a significant effect of age, with lower scores observed in early childhood and adulthood, compared to childhood. Furthermore, individuals with Sotos syndrome appear to display a trait profile that is similar to that identified in ASD. Overall, these findings indicate that the majority of individuals with Sotos syndrome display clinically significant behavioural symptomatology associated with ASD. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United Kingdom | 3 | 60% |
Canada | 1 | 20% |
Unknown | 1 | 20% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 3 | 60% |
Scientists | 2 | 40% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 82 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 11 | 13% |
Student > Master | 10 | 12% |
Researcher | 9 | 11% |
Student > Bachelor | 8 | 10% |
Other | 8 | 10% |
Other | 12 | 15% |
Unknown | 24 | 29% |
Readers by discipline | Count | As % |
---|---|---|
Psychology | 19 | 23% |
Medicine and Dentistry | 12 | 15% |
Neuroscience | 7 | 9% |
Biochemistry, Genetics and Molecular Biology | 5 | 6% |
Social Sciences | 5 | 6% |
Other | 9 | 11% |
Unknown | 25 | 30% |