| Title |
The immunomodulator PSK induces in vitro cytotoxic activity in tumour cell lines via arrest of cell cycle and induction of apoptosis
|
|---|---|
| Published in |
BMC Cancer, March 2008
|
| DOI | 10.1186/1471-2407-8-78 |
| Pubmed ID | |
| Authors |
Eva Jiménez-Medina, Enrique Berruguilla, Irene Romero, Ignacio Algarra, Antonia Collado, Federico Garrido, Angel Garcia-Lora |
| Abstract |
Protein-bound polysaccharide (PSK) is derived from the CM-101 strain of the fungus Coriolus versicolor and has shown anticancer activity in vitro and in in vivo experimental models and human cancers. Several randomized clinical trials have demonstrated that PSK has great potential in adjuvant cancer therapy, with positive results in the adjuvant treatment of gastric, esophageal, colorectal, breast and lung cancers. These studies have suggested the efficacy of PSK as an immunomodulator of biological responses. The precise molecular mechanisms responsible for its biological activity have yet to be fully elucidated. |
X Demographics
The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Venezuela, Bolivarian Republic of | 1 | 50% |
| Unknown | 1 | 50% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 2 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 68 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Brazil | 1 | 1% |
| India | 1 | 1% |
| United Kingdom | 1 | 1% |
| China | 1 | 1% |
| United States | 1 | 1% |
| Unknown | 63 | 93% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 19 | 28% |
| Student > Master | 8 | 12% |
| Student > Ph. D. Student | 7 | 10% |
| Student > Doctoral Student | 6 | 9% |
| Student > Bachelor | 6 | 9% |
| Other | 15 | 22% |
| Unknown | 7 | 10% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 21 | 31% |
| Agricultural and Biological Sciences | 18 | 26% |
| Biochemistry, Genetics and Molecular Biology | 8 | 12% |
| Immunology and Microbiology | 6 | 9% |
| Pharmacology, Toxicology and Pharmaceutical Science | 4 | 6% |
| Other | 4 | 6% |
| Unknown | 7 | 10% |
Attention Score in Context
This research output has an Altmetric Attention Score of 6. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 29 September 2023.
All research outputs
#6,333,017
of 25,071,270 outputs
Outputs from BMC Cancer
#1,565
of 8,864 outputs
Outputs of similar age
#26,379
of 92,072 outputs
Outputs of similar age from BMC Cancer
#4
of 13 outputs
Altmetric has tracked 25,071,270 research outputs across all sources so far. This one has received more attention than most of these and is in the 74th percentile.
So far Altmetric has tracked 8,864 research outputs from this source. They receive a mean Attention Score of 4.6. This one has done well, scoring higher than 82% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 92,072 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 71% of its contemporaries.
We're also able to compare this research output to 13 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 76% of its contemporaries.