Title |
Navigation rules for vessels and neurons: cooperative signaling between VEGF and neural guidance cues
|
---|---|
Published in |
Cellular and Molecular Life Sciences, March 2013
|
DOI | 10.1007/s00018-013-1278-4 |
Pubmed ID | |
Authors |
Sophie Chauvet, Katja Burk, Fanny Mann |
Abstract |
Many organs, such as lungs, nerves, blood and lymphatic vessels, consist of complex networks that carry flows of information, gases, and nutrients within the body. The morphogenetic patterning that generates these organs involves the coordinated action of developmental signaling cues that guide migration of specialized cells. Precision guidance of endothelial tip cells by vascular endothelial growth factors (VEGFs) is well established, and several families of neural guidance molecules have been identified to exert guidance function in both the nervous and the vascular systems. This review discusses recent advances in VEGF research, focusing on the emerging role of neural guidance molecules as key regulators of VEGF function during vascular development and on the novel role of VEGFs in neural cell migration and nerve wiring. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Spain | 1 | 1% |
Israel | 1 | 1% |
Sweden | 1 | 1% |
China | 1 | 1% |
Unknown | 75 | 95% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 24 | 30% |
Researcher | 14 | 18% |
Student > Master | 9 | 11% |
Student > Bachelor | 7 | 9% |
Student > Doctoral Student | 5 | 6% |
Other | 9 | 11% |
Unknown | 11 | 14% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 26 | 33% |
Neuroscience | 10 | 13% |
Biochemistry, Genetics and Molecular Biology | 9 | 11% |
Medicine and Dentistry | 8 | 10% |
Computer Science | 2 | 3% |
Other | 9 | 11% |
Unknown | 15 | 19% |