| Title |
Analysis of Fecal Lactobacillus Community Structure in Patients with Early Rheumatoid Arthritis
|
|---|---|
| Published in |
Current Microbiology, March 2013
|
| DOI | 10.1007/s00284-013-0338-1 |
| Pubmed ID | |
| Authors |
Xiaofei Liu, Qinghua Zou, Benhua Zeng, Yongfei Fang, Hong Wei |
| Abstract |
The objective of this study was to analyze human fecal Lactobacillus community and its relationship with rheumatoid arthritis. Samples taken from rheumatoid arthritis (RA) patients and healthy individuals were analyzed by quantitative real-time PCR. Bacterial DNA was extracted from feces, and amplicons of the Lactobacillus-specific regions of 16S rRNA were analyzed by denaturing gradient gel electrophoresis. The richness, Shannon-Wiener index, and evenness of gut microbiota of both groups were analyzed to compare fecal Lactobacillus community structures. Results of this study demonstrated that fecal microbiota of RA patients contained significantly more Lactobacillus (10.62 ± 1.72 copies/g) than the control group (8.93 ± 1.60 copies/g). Significant increases were observed in RA patients in terms of the richness, Shannon-Wiener, and evenness measures, indicating more bacterial species, and increased bacterial diversity and abundance. These results suggest a potential relationship between Lactobacillus communities and the development and progression of rheumatoid arthritis. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 151 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Japan | 1 | <1% |
| Netherlands | 1 | <1% |
| Sweden | 1 | <1% |
| Russia | 1 | <1% |
| Unknown | 147 | 97% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 27 | 18% |
| Researcher | 24 | 16% |
| Student > Master | 18 | 12% |
| Student > Bachelor | 18 | 12% |
| Other | 8 | 5% |
| Other | 24 | 16% |
| Unknown | 32 | 21% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 32 | 21% |
| Agricultural and Biological Sciences | 25 | 17% |
| Biochemistry, Genetics and Molecular Biology | 19 | 13% |
| Immunology and Microbiology | 18 | 12% |
| Nursing and Health Professions | 6 | 4% |
| Other | 11 | 7% |
| Unknown | 40 | 26% |
Attention Score in Context
This research output has an Altmetric Attention Score of 10. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 20 September 2023.
All research outputs
#3,674,314
of 25,654,806 outputs
Outputs from Current Microbiology
#104
of 2,676 outputs
Outputs of similar age
#29,797
of 209,551 outputs
Outputs of similar age from Current Microbiology
#1
of 20 outputs
Altmetric has tracked 25,654,806 research outputs across all sources so far. Compared to these this one has done well and is in the 85th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 2,676 research outputs from this source. They receive a mean Attention Score of 3.0. This one has done particularly well, scoring higher than 96% of its peers.
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We're also able to compare this research output to 20 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 95% of its contemporaries.