| Title |
COMPULS: design of a multicenter phenotypic, cognitive, genetic, and magnetic resonance imaging study in children with compulsive syndromes
|
|---|---|
| Published in |
BMC Psychiatry, October 2016
|
| DOI | 10.1186/s12888-016-1072-6 |
| Pubmed ID | |
| Authors |
Jilly Naaijen, Saskia de Ruiter, Marcel P. Zwiers, Jeffrey C. Glennon, Sarah Durston, David J. Lythgoe, Steven C. R. Williams, Tobias Banaschewski, Daniel Brandeis, Barbara Franke, Jan K. Buitelaar |
| Abstract |
Compulsivity, the closely linked trait impulsivity and addictive behaviour are associated with several neurodevelopmental disorders, including attention-deficit/hyperactivity disorder (ADHD), autism spectrum disorder (ASD), and obsessive compulsive disorder (OCD). All three disorders show impaired fronto-striatal functioning, which may be related to altered glutamatergic signalling. Genetic factors are also thought to play an important role in the aetiology of compulsivity-related disorders. The COMPULS study is a multi-center study designed to investigate the relationship between the traits compulsivity, impulsivity, and, to a lesser extent, addictive behaviour within and across the neurodevelopmental disorders ADHD, ASD, and OCD. This will be done at the phenotypic, cognitive, neural, and genetic level. In total, 240 participants will take part in COMPULS across four different sites in Europe. Data collection will include diagnostic interviews, behavioural questionnaires, cognitive measures, structural, functional and spectral neuroimaging, and genome-wide genetic information. The COMPULS study will offer the unique opportunity to investigate several key aspects of compulsivity across a large cohort of ADHD, ASD and OCD patients. |
X Demographics
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Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Canada | 1 | 50% |
| Unknown | 1 | 50% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Scientists | 1 | 50% |
| Members of the public | 1 | 50% |
Mendeley readers
The data shown below were compiled from readership statistics for 96 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 1% |
| Unknown | 95 | 99% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 18 | 19% |
| Student > Master | 16 | 17% |
| Student > Bachelor | 9 | 9% |
| Other | 8 | 8% |
| Researcher | 7 | 7% |
| Other | 15 | 16% |
| Unknown | 23 | 24% |
| Readers by discipline | Count | As % |
|---|---|---|
| Psychology | 20 | 21% |
| Neuroscience | 17 | 18% |
| Medicine and Dentistry | 12 | 13% |
| Nursing and Health Professions | 5 | 5% |
| Agricultural and Biological Sciences | 5 | 5% |
| Other | 8 | 8% |
| Unknown | 29 | 30% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 01 November 2016.
All research outputs
#17,823,285
of 22,896,955 outputs
Outputs from BMC Psychiatry
#3,701
of 4,710 outputs
Outputs of similar age
#223,969
of 314,045 outputs
Outputs of similar age from BMC Psychiatry
#81
of 96 outputs
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