| Title |
An HPV 16 L1-based chimeric human papilloma virus-like particles containing a string of epitopes produced in plants is able to elicit humoral and cytotoxic T-cell activity in mice
|
|---|---|
| Published in |
Virology Journal, January 2009
|
| DOI | 10.1186/1743-422x-6-2 |
| Pubmed ID | |
| Authors |
Georgina Paz de la Rosa, Alberto Monroy-García, María de Lourdes Mora-García, Cristina Gehibie Reynaga Peña, Jorge Hernández-Montes, Benny Weiss-Steider, Miguel Angel Gómez Lim |
| Abstract |
Even though two prophylactic vaccines against HPV are currently licensed, infections by the virus continue to be a major health problem mainly in developing countries. The cost of the vaccines limits wide-scale application in poor countries. A promising strategy for producing affordable and efficient vaccines involves the expression of recombinant immunogens in plants. Several HPV genes have been expressed in plants, including L1, which can self-assemble into virus-like particles. A plant-based, dual prophylactic/therapeutic vaccine remains an attractive possibility. |
Mendeley readers
The data shown below were compiled from readership statistics for 71 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Italy | 1 | 1% |
| Argentina | 1 | 1% |
| Unknown | 69 | 97% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 16 | 23% |
| Student > Master | 13 | 18% |
| Researcher | 10 | 14% |
| Student > Doctoral Student | 7 | 10% |
| Student > Bachelor | 7 | 10% |
| Other | 5 | 7% |
| Unknown | 13 | 18% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 25 | 35% |
| Biochemistry, Genetics and Molecular Biology | 9 | 13% |
| Medicine and Dentistry | 8 | 11% |
| Engineering | 6 | 8% |
| Immunology and Microbiology | 2 | 3% |
| Other | 7 | 10% |
| Unknown | 14 | 20% |
Attention Score in Context
This research output has an Altmetric Attention Score of 7. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 12 April 2016.
All research outputs
#4,579,649
of 22,701,287 outputs
Outputs from Virology Journal
#452
of 3,031 outputs
Outputs of similar age
#25,727
of 169,300 outputs
Outputs of similar age from Virology Journal
#7
of 36 outputs
Altmetric has tracked 22,701,287 research outputs across all sources so far. Compared to these this one has done well and is in the 79th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 3,031 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 25.6. This one has done well, scoring higher than 84% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 169,300 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 84% of its contemporaries.
We're also able to compare this research output to 36 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 77% of its contemporaries.