| Title |
Co-localisation and secretion of glucagon-like peptide 1 and peptide YY from primary cultured human L cells
|
|---|---|
| Published in |
Diabetologia, March 2013
|
| DOI | 10.1007/s00125-013-2887-z |
| Pubmed ID | |
| Authors |
A. M. Habib, P. Richards, G. J. Rogers, F. Reimann, F. M. Gribble |
| Abstract |
Targeting the secretion of gut peptides such as glucagon-like peptide 1 (GLP-1) and peptide YY (PYY) is a strategy under development for the treatment of diabetes and obesity, aiming to mimic the beneficial alterations in intestinal physiology that follow gastric bypass surgery. In vitro systems are now well established for studying the mouse enteroendocrine system, but whether these accurately model the human gut remains unclear. The aim of this study was to establish and characterise human primary intestinal cultures as a model for assessing GLP-1 and PYY secretion in vitro. |
X Demographics
The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Japan | 1 | 50% |
| Unknown | 1 | 50% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 50% |
| Scientists | 1 | 50% |
Mendeley readers
The data shown below were compiled from readership statistics for 127 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Spain | 2 | 2% |
| United Kingdom | 2 | 2% |
| Netherlands | 1 | <1% |
| France | 1 | <1% |
| Sweden | 1 | <1% |
| Egypt | 1 | <1% |
| Japan | 1 | <1% |
| Unknown | 118 | 93% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 27 | 21% |
| Researcher | 22 | 17% |
| Student > Bachelor | 11 | 9% |
| Professor > Associate Professor | 11 | 9% |
| Student > Doctoral Student | 10 | 8% |
| Other | 22 | 17% |
| Unknown | 24 | 19% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 29 | 23% |
| Agricultural and Biological Sciences | 23 | 18% |
| Biochemistry, Genetics and Molecular Biology | 18 | 14% |
| Pharmacology, Toxicology and Pharmaceutical Science | 12 | 9% |
| Chemistry | 5 | 4% |
| Other | 11 | 9% |
| Unknown | 29 | 23% |
Attention Score in Context
This research output has an Altmetric Attention Score of 10. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 12 May 2020.
All research outputs
#3,049,593
of 22,701,287 outputs
Outputs from Diabetologia
#1,462
of 5,026 outputs
Outputs of similar age
#26,507
of 197,452 outputs
Outputs of similar age from Diabetologia
#12
of 54 outputs
Altmetric has tracked 22,701,287 research outputs across all sources so far. Compared to these this one has done well and is in the 86th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 5,026 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 22.6. This one has gotten more attention than average, scoring higher than 70% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 197,452 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 86% of its contemporaries.
We're also able to compare this research output to 54 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 77% of its contemporaries.