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Ontogenic changes in human placental sodium iodide symporter expression

Overview of attention for article published in Placenta, September 2012
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Title
Ontogenic changes in human placental sodium iodide symporter expression
Published in
Placenta, September 2012
DOI 10.1016/j.placenta.2012.08.002
Pubmed ID
Authors

H. Li, J. Patel, R.H. Mortimer, K. Richard

Abstract

The human fetus requires a maternal supply of iodide to synthesize thyroid hormone from 16 weeks gestation. Placental iodide transport is regulated by the sodium iodide symporter (NIS). We studied the ontogeny of NIS in placentas from surgically terminated pregnancies and from normal term pregnancies. NIS mRNA was low at 6 weeks gestation and peaked at 12 weeks gestation. Placental NIS protein levels are significantly correlated with gestational age during early pregnancy and increase with increased placental vascularization. This would lead to increased iodide supply to meet increased fetal requirements for thyroid hormone synthesis as the pregnancy progresses.

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X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 16 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 16 100%

Demographic breakdown

Readers by professional status Count As %
Student > Postgraduate 3 19%
Other 2 13%
Student > Doctoral Student 2 13%
Student > Master 2 13%
Lecturer > Senior Lecturer 1 6%
Other 3 19%
Unknown 3 19%
Readers by discipline Count As %
Medicine and Dentistry 9 56%
Agricultural and Biological Sciences 1 6%
Chemistry 1 6%
Engineering 1 6%
Unknown 4 25%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 23 March 2013.
All research outputs
#22,756,649
of 25,371,288 outputs
Outputs from Placenta
#1,466
of 2,026 outputs
Outputs of similar age
#168,587
of 187,199 outputs
Outputs of similar age from Placenta
#14
of 21 outputs
Altmetric has tracked 25,371,288 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 2,026 research outputs from this source. They receive a mean Attention Score of 4.9. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 187,199 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 21 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.