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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Genetics of prion diseases
|
|---|---|
| Published in |
Current Opinion in Genetics & Development, March 2013
|
| DOI | 10.1016/j.gde.2013.02.012 |
| Pubmed ID | |
| Authors |
Sarah E Lloyd, Simon Mead, John Collinge |
| Abstract |
Prion diseases are transmissible, fatal neurodegenerative diseases that include scrapie and bovine spongiform encephalopathy (BSE) in animals and Creutzfeldt-Jakob disease (CJD) in human. The prion protein gene (PRNP) is the major genetic determinant of susceptibility, however, several studies now suggest that other genes are also important. Two recent genome wide association studies in human have identified four new loci of interest: ZBTB38-RASA2 in UK CJD cases and MTMR7 and NPAS2 in variant CJD. Complementary studies in mouse have used complex crosses to identify new modifiers such as Cpne8 and provided supporting evidence for previously implicated genes (Rarb and Stmn2). Expression profiling has identified new candidates, including Hspa13, which reduces incubation time in a transgenic model. |
X Demographics
The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Australia | 1 | 50% |
| Unknown | 1 | 50% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Scientists | 1 | 50% |
| Members of the public | 1 | 50% |
Mendeley readers
The data shown below were compiled from readership statistics for 147 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Portugal | 1 | <1% |
| France | 1 | <1% |
| United Kingdom | 1 | <1% |
| Canada | 1 | <1% |
| China | 1 | <1% |
| Japan | 1 | <1% |
| United States | 1 | <1% |
| Unknown | 140 | 95% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 28 | 19% |
| Student > Ph. D. Student | 27 | 18% |
| Researcher | 27 | 18% |
| Student > Master | 17 | 12% |
| Other | 8 | 5% |
| Other | 29 | 20% |
| Unknown | 11 | 7% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 44 | 30% |
| Biochemistry, Genetics and Molecular Biology | 31 | 21% |
| Neuroscience | 19 | 13% |
| Medicine and Dentistry | 17 | 12% |
| Immunology and Microbiology | 4 | 3% |
| Other | 16 | 11% |
| Unknown | 16 | 11% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 26 March 2013.
All research outputs
#17,286,379
of 25,374,647 outputs
Outputs from Current Opinion in Genetics & Development
#1,452
of 1,740 outputs
Outputs of similar age
#135,211
of 210,228 outputs
Outputs of similar age from Current Opinion in Genetics & Development
#12
of 19 outputs
Altmetric has tracked 25,374,647 research outputs across all sources so far. This one is in the 21st percentile – i.e., 21% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,740 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 7.0. This one is in the 13th percentile – i.e., 13% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 210,228 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 26th percentile – i.e., 26% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 19 others from the same source and published within six weeks on either side of this one. This one is in the 15th percentile – i.e., 15% of its contemporaries scored the same or lower than it.